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ProteomicsUveal melanoma cell lines are representative for their tumour, except cell lines Mel285 and Mel290: the odd two out
Purpose: In uveal melanoma (UM) research, several cell lines are used in preclinical studies. Because Mel285 and Mel290 do not harbour typical GNAQ or GNA11 hotspot mutations, we aimed at better classifying them and understanding if we could find genetic causes to explain their protein and mRNA expr...
ORGANISM(S): Homo sapiens (Human) 
2024-07-16 | PXD051055 | Pride
G protein subunit alpha Mel285 Uveal melanoma Mel290 Cnas 
UnknownProtein and mRNA Expression in Uveal Melanoma Cell Lines Are Related to GNA and BAP1 Mutation Status.
Not available
S-EPMC11268447 | biostudies-literature
Genomics
Transcriptome change of 92.1 and Mel285 upon elesclomol treatment
PRJNA733836 | ENA
GenomicsAdipophilin as a metabolic biomarker for Uveal Melanoma
Adipophilin as a metabolic biomarker for Uveal Melanoma
PRJNA935315 | ENA
UnknownThe Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach.
Not available
S-EPMC6770058 | biostudies-literature
UnknownHypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation.
Not available
S-EPMC4148307 | biostudies-literature
UnknownHigh Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells.
Not available
S-EPMC7600582 | biostudies-literature
GenomicsIn uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations
In uveal melanoma Gα-protein GNA11 mutations convey a shorter disease-specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than Gα-protein GNAQ mutations
PRJNA811514 | ENA
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