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TranscriptomicsEffect of acute creatine monohydrate supplementation on skeletal muscle transcriptome
Expression profiling of vastus lateralis muscle of young, healthy, non-obese men supplemented with creatine monohydrate vs. placebo for 10 days. Results identify transcriptional pathways activated in skeletal muscles as a result of acute creatine monohydrate supplementation. Keywords: Supplementatio...
ORGANISM(S): Homo sapiens 
2010-06-11 | E-GEOD-7877 | biostudies-arrayexpress
TranscriptomicsLimb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women
Advancements in animal models and cell culture techniques have been invaluable in the elucidation of molecular events and mechanisms regulating muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine a...
ORGANISM(S): Homo sapiens 
2009-02-21 | E-GEOD-14901 | biostudies-arrayexpress
TranscriptomicsEccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways
Full title: Eccentric exercise activates novel transcriptional regulation of hypertrophic signaling pathways not affected by hormone changes. Unaccustomed eccentric exercise damages muscle tissue stimulating mechanisms of recovery and remodeling that may be affected by cellular protection by the sex...
ORGANISM(S): Homo sapiens 
2009-12-16 | E-GEOD-19062 | biostudies-arrayexpress
TranscriptomicsAge-related behaviors have distinct transcriptional profiles in C. elegans
There has been a great deal of interest in identifying potential biomarkers of aging (Butler et al. 2004). Biomarkers of aging would be useful to predict potential vulnerabilities in an individual that may arise well before they are chronologically expected, due to idiosyncratic aging rates that occ...
ORGANISM(S): Caenorhabditis elegans 
2008-09-16 | E-GEOD-12290 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans aging in 5 individuals of each age (4,9,14,or 19 days) of each of two genotypes (N2 or daf-2)N2 daf-2
Gene expression profiles were generated for 4-5 individuals of each age (4,9,14,or 19 days) of each of two genotypes (N2 or daf-2)
ORGANISM(S): Caenorhabditis elegans 
2009-07-01 | E-MEXP-138 | biostudies-arrayexpress
TranscriptomicscDNA microarray analysis of human skeletal muscle after endurance exercise
We examined global mRNA expression using cDNA microarrays in skeletal muscle of humans before, and 3h and 48h after a single bout of exhaustive endurance exercise (cycling). Keywords: Time course Healthy, non-trained university-aged subjects performed a single bout of exhaustive cycling. Skeletal ...
ORGANISM(S): Homo sapiens 
2006-02-17 | E-GEOD-4247 | biostudies-arrayexpress
TranscriptomicsInsulin-like Signaling Determines Survival During Stress via Post Transcriptional Mechanisms in C. elegans.
The insulin-like signaling (ILS) pathway regulates metabolism and is known to modulate adult lifespan in C. elegans. Altered stress responses and resistance to a wide range of stressors are also associated with changes in ILS and contribute to enhanced longevity. The transcription factors DAF-16 and...
ORGANISM(S): Caenorhabditis elegans 
2010-06-17 | E-GEOD-22383 | biostudies-arrayexpress
UnknownCellular Senescence Mediates Doxorubicin Chemotherapy-Induced Aortic Stiffening: Role of Glycation Stress.
Not available
S-EPMC12327803 | biostudies-literature
UnknownCellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment.
Not available
S-EPMC10530538 | biostudies-literature
UnknownSingle cell gene expression profiling of cortical osteoblast lineage cells.
Not available
S-EPMC3589579 | biostudies-literature
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