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Human reticulocytes were enriched from human umbilical blood, and cultured in vitro for the production of reticulocyte-derived exosomes (HuRex)to unveil their proteomic composition. As research on the molecular-cargo of exosomes is largely confounded by the lack of a “gold-standard” methodology, we ...
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD008545 | Pride
This project focused in the proteomic characterization of plasma-derived exosomes from Plasmodium vivax infected FRG huHep mice, a suitable in vivo model for the development of pre-erythrocytic stages of this parasite. P. vivax is responsible for the vast majority of Malaria cases outside Africa. Th...
ORGANISM(S): Plasmodium vivax Homo sapiens (Human) Mus musculus (Mouse) 
2018-07-16 | PXD008945 | Pride
Expression profiling is a well established tool for the genome-wide analysis of the transcriptional activity of human neoplasia. However, the high sensitivity of this approach combined with the well-known cellular and molecular heterogeneity of cancer often result in extremely complex and extended e...
ORGANISM(S): Homo sapiens 
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