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modENCODE_submission_2600 This submission comes from a modENCODE project of Michael Snyder. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We are identifying the DNA binding sites for 300 transcription factors in C. elegans. Each transcription factor gene is ta...
ORGANISM(S): Caenorhabditis elegans 
LET-418/Mi-2 is an ATP-dependent chromatin remodeler and is part of large complexes like the NuRD complex which are repressive complex and has a role in vulval development in Caenorhabditis elegans. Along with MEP-1, LET-418 also forms the MEC complex which functions in the post embryonic developmen...
ORGANISM(S): Caenorhabditis elegans 
DamID in intestinal tissue of young adults of C. elegans hermaphrodites to decipher the binding target sites for LET-418 and MEP-1
Expression data from Caenorhabditis elegans let-418(RNAi), mep-1(RNAi) and gfp(RNAi) L1 larvae. The C. elegans genome encodes two homologs of the human protein Mi-2, namely LET-418 and CHD-3. LET-418 plays an essential role during development; its depletion leads to a pleiotropic and lethal phenotyp...
ORGANISM(S): Caenorhabditis elegans 
In eukaryotes, trimethylation of lysine 9 on histone H3 (H3K9) is associated with transcriptional silencing of transposable elements (TEs). In drosophila ovaries, this heterochromatic repressive mark is thought to be deposited by SetDB1 on TE genomic loci after the initial recognition of nascent tra...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-07-21 | PXD018749 | Pride
The Dream and MEC Complexes reinforce SPR-5 MET-2 maternal reprogramming to maintain the Germline-Soma distinction [mep-1 RNAseq]
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