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ProteomicsProteomics, post-translational modifications, and integrative analyses reveal heterogeneity of molecular mechanisms within medulloblastoma subgroups
Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Francois JP, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA,...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-07-20 | MSV000082644 | MassIVE
TranscriptomicsRibonomic analysis of human Pum1 in HeLa cells
PUF family proteins are among the best characterized regulatory RNA-binding proteins in non-mammalian species, but relatively little is known about mRNA targets or functions of mammalian PUF proteins. In this study, we used ribonomic analysis to identify and analyze mRNAs associated with ribonucleo...
ORGANISM(S): Homo sapiens 
2008-05-01 | E-GEOD-11301 | biostudies-arrayexpress
TranscriptomicsExpression data from DHT stimulation vs. control in LNCaP cells
Expression data from DHT stimulation vs. control in LNCaP cells LNCaP cells were maintained in phenol red-free RPMI supplemented with 10% charcoal/dextran stripped FCS for three days before stimulation with 100 nM dihydrotestosterone (DHT) for 48 hours
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-14988 | biostudies-arrayexpress
TranscriptomicsBJAB Cell Lines Unmodified, Transduced with ith lentiviral vector pNL-SIN-CMV-AcGFP or pNL-SIN-CMV-AcGFP/miR-K12-11
All metazoan eukaryotes express microRNAs (miRNAs), ~22 nt long regulatory RNAs that can repress the expression of mRNAs bearing complementary sequences. Several DNA viruses also express miRNAs in infected cells, suggesting a role in viral replication and pathogenesis. While specific viral miRNAs ha...
ORGANISM(S): Homo sapiens 
2007-12-18 | E-GEOD-8867 | biostudies-arrayexpress
TranscriptomicsExpression data from ERBB2 over-expression and EGF stimulation in MCF10A cells
Expression data from ERBB2 over-expression and EGF stimulation in MCF10A cells The cells were transduced with retroviruses encoding vector control (pBabe) or pBabe-ErbB2. After infection cells were switched to assay medium supplemented with only 2% horse serum and no EGF. For EGF stimulation, cells ...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-14987 | biostudies-arrayexpress
TranscriptomicscaArray_golub-00299: Chemosensitivity prediction by transcriptional profiling
In an effort to develop a genomics-based approach to the prediction of drug response, we have developed an algorithm for classification of cell line chemosensitivity based on gene expression profiles alone. Using oligonucleotide microarrays, the expression levels of 6,817 genes were measured in a pa...
ORGANISM(S): Homo sapiens 
2015-05-16 | E-GEOD-68936 | biostudies-arrayexpress
UnknownCompendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation.
Not available
S-EPMC5330663 | biostudies-literature
ProteomicsMedulloblastoma Patient-Derived Xenograft Proteomics
Proteomic and phosphoproteomic characterization of 20 orthotopic patient-derived xenograft models of medulloblastoma
ORGANISM(S): Homo sapiens (Human) 
2022-09-01 | PXD035070 | Pride
Proteomics Medulloblastoma Phosphoproteomics Patient-derived xenograft (pdx) Lc-ms/ms 
GenomicsGenomic Sequencing of Medulloblastoma

Medulloblastomas are the most common malignant brain tumors in children. Identifying and understanding the genetic events that drive these tumors is critical for the development of more effective diagnostic, prognostic and therapeutic strategies. Recently, our group and others described distinct ...

phs000504.v1.p1 | EGA
UnknownA Curated Resource for Phosphosite-specific Signature Analysis.
Not available
S-EPMC6398202 | biostudies-literature
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