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MetabolomicsMetabolically-incorporated deuterium in myelin localized by neutron diffraction and identified by mass spectrometry
Myelin is a natural and dynamic multilamellar membrane structure that continues to be of significant biological and neurological interest, especially with respect to its biosynthesis and assembly during its normal formation and maintenance, and pathological breakdown. To explore the usefulness of ne...
2024-09-27 | MTBLS4717 | MetaboLights
Genomicsm6A-Label-seq directly reports m6A methylome at base resolution
m6A-Label-seq directly reports m6A methylome at base resolution
PRJNA543237 | ENA
TranscriptomicsGene expression data from human subcutaneous adipose tissue
Obesity is a heterogeneous conditions comprising obese individuals with metabolic disorders (termed metabolically unhealthy obese; MUO) and obese individuals who are metabolically healthy (termed metabolically healthy obese; MHO). We used microarrays to examine differences in subcutaneous adipose ti...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-55200 | biostudies-arrayexpress
TranscriptomicsThe effects of moderate weight gain in adipose tissue gene expression in metabolically-normal (MNO) and metabolically-abnormal (MAO) subjects
Obesity is associated with insulin resistance and increased intrahepatic triglyceride (IHTG) content, which are key risk factors for diabetes and cardiovascular disease. However, a subset of obese people does not develop these metabolic complications. We tested the hypothesis that MNO, but not MAO, ...
ORGANISM(S): Homo sapiens 
2015-01-09 | E-GEOD-62832 | biostudies-arrayexpress
GenomicsRNA-seq of metabolically labelled RNA by 4-thiouracil from mouse tissues
RNA-seq of metabolically labelled RNA by 4-thiouracil from mouse tissues
PRJEB24362 | ENA
UnknownProinflammatory and lipid biomarkers mediate metabolically healthy obesity: A proteomics study.
Not available
S-EPMC4882259 | biostudies-literature
TranscriptomicsGene expression of metabolically adaptable triple-negative breast cancer cells
To gain insight into the characteristic of metabolically adaptable MA cells that enables them to survive severe metabolic challenge, i.e., prolonged lack of glutamine and other challenges [Singh et al., PLoS ONE 7: e36510, 2012], we used gene expression microarrays to compare these cells with the pa...
ORGANISM(S): Homo sapiens 
2014-10-03 | E-GEOD-60016 | biostudies-arrayexpress
UnknownA New Method for Ethical and Efficient Evidence Generation for Off-Label Medication Use in Oncology (A Case Study in Glioblastoma).
Not available
S-EPMC6610246 | biostudies-literature
UnknownProbing single-cell metabolism reveals prognostic value of highly metabolically active circulating stromal cells in prostate cancer.
Not available
S-EPMC7527228 | biostudies-literature
TranscriptomicsRNA-seq of metabolically labelled RNA by 4-thiouracil from mouse tissues
To identify cell type-specific RNA without cell sorting, mice expressing UPRT in a specific cell type were exposed to 4-thiouracil to label RNA only in the UPRT-expressing cells. Total RNA was extracted from tissues and treated with iodoacetamide followed by RNA-seq library preparation. The reads ge...
ORGANISM(S): Mus musculus 
2018-07-09 | E-MTAB-6353 | biostudies-arrayexpress
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