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MetabolomicsMetabolomic correlation-network modules in Arabidopsis based on a graph-clustering approach
Deciphering the metabolome is essential for a better understanding of the cellular metabolism as a system. Typical metabolomics data show a few but significant correlations among metabolite levels when data sampling is repeated across individuals grown under strictly controlled conditions. Although ...
2014-03-01 | MTBLS45 | MetaboLights
TranscriptomicsMetabolomic heterogeneity of severe pulmonary arterial hypertension
Although multiple gene and protein expression have been extensively profiled in human pulmonary arterial hypertension (PAH), the mechanism for the development and progression of pulmonary hypertension remains elusive. Analysis of the global metabolomic heterogeneity within the pulmonary vascular sy...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-53408 | biostudies-arrayexpress
MetabolomicsMetabolomic Characterization of Knock-Out Mutants in Arabidopsis - Development of a Metabolite Profiling Database for Knock-Out Mutants in Arabidopsis (MeKO)
Despite recent intensive research efforts in functional genomics, the functions of only a limited number of Arabidopsis (Arabidopsis thaliana) genes have been determined experimentally. Thus, improving gene annotation remains a major challenge in plant science. Because metabolite profiling can chara...
2014-03-01 | MTBLS47 | MetaboLights
MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
MetabolomicsSerum metabolomic profiles for distinguishing lung cancer from pulmonary tuberculosis: identification of rapid and noninvasive biomarker

BACKGROUND: Pulmonary tuberculosis (TB) and lung cancer (LC) have similar clinical symptoms and atypical imaging findings which are easily misdiagnosed. There is an urgent need for a noninvasive, rapid and accurate biomarker for distinguishing LC from TB.

METHODS:

2024-01-16 | MTBLS6990 | MetaboLights
MetabolomicsArginine-induced metabolomic perturbation in Streptococcus mutans

BACKGROUND: Streptococcus mutans is a major pathogen responsible for dental caries. Arginine is a promising potential caries preventive agent which can inhibit the growth of S. mutans. However, the mechanism whereby arginine inhibits S. mutans growth r...

2023-10-20 | MTBLS3020 | MetaboLights
MetabolomicsUrinary Extracellular Vesicle Metabolomic Profiling Reveals a Distinct Molecular Signature for the Non-Invasive Diagnosis of Lupus Nephritis

Background: Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), underscoring an urgent need for non-invasive diagnostic biomarkers. 

Objective: This study aimed to define the metabolomic signature of urinary e...

2026-02-11 | MTBLS13839 | MetaboLights
MetabolomicsFlavonoid-targeted metabolomic analysis.

Flavonoids, one of the major groups of root exudates, are active molecules mediating plant-PGPR interactions. Flavonoids can alleviate nutrient deficiencies and drought stress to maintain normal plant growth. Here, We used flavonoid targeted metabolomic analysis to profile flavonoid components an...

2025-12-14 | MTBLS13507 | MetaboLights
MetabolomicsMetabolomic analysis of metabolic differences between NSD1 wild-type and NSD1 knockout endometrial cancer cells

Metabolomic analysis of metabolic differences between NSD1 wild-type and NSD1 knockout endometrial cancer cells

2026-01-21 | MTBLS13567 | MetaboLights
MetabolomicsA serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome
Antiphospholipid syndrome (APS) is a rheumatic inflammatory chronic autoimmune disease inducing hypercoagulable state associated with vascular thrombosis and pregnancy loss in women. Cardiac, cerebral and vascular strokes in these patients are responsible for reduction in life expectancy. Timely dia...
2017-09-06 | MTBLS356 | MetaboLights
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