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ProteomicsTbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
The African trypanosome Trypanosoma brucei is a unicellular eukaryote, which relies on a protective Variant Surface Glycoprotein (VSG) coat for survival in the mammalian host. A single trypanosome has >2000 VSG genes and pseudogenes of which only one is expressed from one of ~15 telomeric bloodstre...
ORGANISM(S): Trypanosoma brucei 
2020-11-06 | PXD022397 | Pride
Lc/ms-ms 
ProteomicsBCAAs modulate the proteomic profile of Pro-induced metacyclics
Trypanosoma cruzi, the etiological agent of Chagas disease, has a complex life cycle occurring between triatomine insects (responsible for the vectorial transmission of the infection) and mammals. Inside the insect vector, epimastigote forms (proliferative, non-infective to mammals) differentiate in...
ORGANISM(S): Trypanosoma cruzi cruzi 
2024-09-28 | PXD049190 | Pride
Bcaa Metacyclogenesis Trypanosoma cruzi 
ProteomicsThe proteome and transcriptome of the infectious metacyclic form of Trypanosoma brucei define quiescent cells primed for mammalian invasion
The infectious metacyclic forms of Trypanosoma brucei result from a complex development in the tsetse fly vThe infectious metacyclic forms of Trypanosoma brucei result from a complex development in the tsetse fly vector. When they infect mammals, they cause African sleeping sickness in humans. Due t...
ORGANISM(S): Trypanosoma brucei 
2017-07-31 | PXD006197 | Pride
Trypanosoma brucei Transcriptome Proteome Metacyclics 
TranscriptomicsSimultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE
Leishmania (L) are intracellular protozoan parasites which are able to survive and replicate within the harsh and potentially hostile phago-lysosomal environment of mammalian mononuclear phagocytes. A complex interplay then takes place between the macrophage (MM-NM-&) striving to eliminate the patho...
ORGANISM(S): Leishmania major 
2008-05-21 | E-GEOD-10442 | biostudies-arrayexpress
TranscriptomicsTbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
The African trypanosome Trypanosoma brucei is a unicellular eukaryote, which relies on a protective Variant Surface Glycoprotein (VSG) coat for survival in the mammalian host. A single trypanosome has >2000 VSG genes and pseudogenes of which only one is expressed from one of ~15 telomeric bloodstrea...
ORGANISM(S): Trypanosoma brucei 
2020-11-04 | GSE160713 | GEO
UnknownTrafficking and release of Leishmania metacyclic HASPB on macrophage invasion.
Not available
S-EPMC3491706 | biostudies-literature
UnknownAttenuation of Leishmania infantum chagasi metacyclic promastigotes by sterol depletion.
Not available
S-EPMC3697599 | biostudies-literature
UnknownSynchronous expression of individual metacyclic variant surface glycoprotein genes in Trypanosoma brucei.
Not available
S-EPMC4470760 | biostudies-literature
GenomicsTbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
TbSAP is a novel chromatin protein repressing metacyclic Variant Surface Glycoprotein expression sites in bloodstream form Trypanosoma brucei
PRJNA674063 | ENA
GenomicsTrypanosoma brucei brucei TREU927
Trypanosoma brucei metacyclic transcriptome
PRJNA381815 | ENA
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