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Metalloproteins are essential for a vast array of biological processes in all living organisms. Identification of multiple metalloproteins from native expression (“metalloproteomics”) based on a single chromatography has low resolution and/or sensitivity, while classical protein purification lacks t...
ORGANISM(S): Glycine max Trichodesmium erythraeum IMS101 
2025-08-25 | PXD056024 | Pride
The natural product holomycin contains a unique cyclic disulfide and exhibits broad-spectrum antimicrobial activities. Reduced holomycin chelates metal ions with high affinity and disrupts metal homeostasis in the cell. To identify cellular metalloproteins that are affected by holomycin, reactive-cy...
ORGANISM(S): Escherichia coli 
2023-08-14 | PXD040777 | Pride
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