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UnknownMetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments.
Not available
S-EPMC7005732 | biostudies-literature
UnknownFumagillin regulates stemness and malignancies in cancer stem-like cells derived from liver cancer via targeting to MetAP-2.
Not available
S-EPMC10381083 | biostudies-literature
ProteomicsASTRAL deep-proteotyping of a human fecal standard to evaluate metaproteomics strategies.
Metaproteomics of a human fecal standard, MetaP, with ASTRAL tandem mass spectometer operated in data-dependent analysis for deep-proteotyping and evaluate metaproteomics strategies.
ORGANISM(S): Balneola vulgaris Homo sapiens (Human) Deinococcus proteolyticus MRP 
2024-03-07 | PXD045838 | Pride
Metaproteomics Proteins Functional analysis Microbiome Gut Proteotyping Taxa 
ProteomicsExploris 480 dataset acquired on a human fecal standard to evaluate metaproteomics strategies.
Metaproteomics of a human fecal standard, MetaP, with an Exploris480 tandem mass spectometer operated in data-dependent analysis for proteotyping and evaluation of metaproteomics strategies.
ORGANISM(S): Homo sapiens (Human) Balneola vulgaris Deinococcus proteolyticus MRP 
2024-03-07 | PXD047139 | Pride
Metaproteomics Proteins Functional analysis Microbiome Gut Proteotyping Taxa 
ProteomicsASTRAL 15 and 30 min in-depth metaproteomics of a human fecal standard to evaluate depth of analysis following a taxonomical proteotyping strategy.
In-depth metaproteomics of a human fecal standard, MetaP, with ASTRAL tandem mass spectometer operated in data-independent acquisition mode for 15 min or 30 min and with a database built following sample taxonomical proteotyping.
ORGANISM(S): Homo sapiens (Human) Balneola vulgaris Deinococcus proteolyticus MRP 
2024-03-07 | PXD046290 | Pride
Metaproteomics Proteins Functional analysis Dia Microbiome Gut Mass spectrometry Proteotyping Taxa 
ProteomicsASTRAL 60 and 90 min in-depth metaproteomics of a human fecal standard to evaluate depth of analysis following a taxonomical proteotyping strategy.
In-depth metaproteomics of a human fecal standard, MetaP, with ASTRAL tandem mass spectometer operated in data-independent acquisition mode for 60 min or 90 min and with a database built following sample taxonomical proteotyping.
ORGANISM(S): Homo sapiens (Human) Balneola vulgaris Deinococcus proteolyticus MRP 
2024-03-07 | PXD046320 | Pride
Metaproteomics Proteins Functional analysis Dia Microbiome Gut Mass spectrometry Proteotyping Taxa 
UnknownComputational validation of 3-ammonio-3-(4-oxido- 1H-imidazol-1-ium-5-yl) propane-1, 1-bis (olate) as a potent anti-tubercular drug against mt-MetAP.
Not available
S-EPMC3489093 | biostudies-literature
ProteomicsAn OMICS perspective on N-terminal Methionine Excision
Excision of the N-terminal initiator methionine (iMet) from nascent peptide chains is an essential and omnipresent protein modification carried out by Methionine aminopetidases (MetAPs) and accounting for a major source of N-terminal proteoform diversity. While MetAP2 is known to be implicated in pr...
ORGANISM(S): Homo sapiens (Human) 
2018-01-10 | PXD006638 | Pride
Metap Metap1 Shotgun N-terminal proteomics Imet excision 
TranscriptomicsOMICS assisted N-terminal proteoform and protein expression profiling upon methionine aminopeptidase 1 (MetAP1) deletion
Excision of the N-terminal initiator methionine (iMet) residue from nascent peptide chains is an essential and omnipresent protein modification carried out by methionine aminopeptidases (MetAPs) that accounts for a major source of N-terminal proteoform diversity. While MetAP2 is known to be implicat...
ORGANISM(S): Homo sapiens 
2018-01-12 | GSE103405 | GEO
UnknownTargeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest.
Not available
S-EPMC1480595 | biostudies-literature
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