Metastatic gastric cancer

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Unknown (1337)
Transcriptomics (175)
Genomics (152)
Clinical (127)
Proteomics (17)
Metabolomics (3)
Genomic (2)
Methylation profiling (2)
Other (2)

Organisms

Homo sapiens (181)
Mus musculus (39)
Campylobacter jejuni (2)
Sus scrofa (2)
Salmonella enterica subsp. enterica serovar Typhimurium (1)
Caenorhabditis elegans (1)
Canis lupus familiaris (1)
Rattus norvegicus (1)
Drosophila melanogaster (1)

Organisms

Homo sapiens (69)
Mus musculus (16)

Repository

biostudies-arrayexpress (128)
ENA (116)
geo (64)
EGA (25)
pride (8)
ExpressionAtlas (3)
iProX (3)
MetaboLights (3)
dbGaP (2)
jPOST (1)
MassIVE (1)

Tissue

Breast (2)
Stomach (2)
Adrenal gland (1)
Blood (1)
Bone marrow (1)
Bone tissue (1)
Brain (1)
Caecum (1)
Cartilage tissue (1)
Chordate pharynx (1)
Colon (1)
Esophagus (1)
Ileum (1)
Kidney (1)
Liver (1)
Lung (1)
Lymph node (1)
Nasal septum (1)
Oral cavity (1)
Ovary (1)
Pancreas (1)
Pleura (1)
Prostate gland (1)
Rectum (1)
Skeletal muscle tissue (1)
Testis (1)
Tongue (1)
Urinary bladder (1)
Uterine cervix (1)
Uterus (1)

Disease

Gastric adenocarcinoma (4)
Glioblastoma (4)
Breast adenocarcinoma (3)
Cervical adenocarcinoma (3)
Colon carcinoma (3)
Hepatocellular carcinoma (3)
Large cell lung carcinoma (3)
Melanoma (3)
Non-small cell lung carcinoma (3)
Ovarian adenocarcinoma (3)
Ovarian carcinoma (3)
Pancreatic adenocarcinoma (3)
Squamous cell lung carcinoma (3)
Acute lymphoblastic leukemia (2)
Acute myeloid leukemia (2)
Anaplastic astrocytoma (2)
Anaplastic large cell lymphoma (2)
Breast carcinoma (2)
Breast ductal adenocarcinoma (2)
Bronchoalveolar adenocarcinoma (2)
Cecum adenocarcinoma (2)
Cervical squamous cell carcinoma (2)
Chondrosarcoma (2)
Chronic myelogenous leukemia (2)
Colon adenocarcinoma (2)
Diffuse large B-cell lymphoma (2)
Erythroleukemia (2)
Gastric adenosquamous carcinoma (2)
Gastric carcinoma (2)
Gastric tubular adenocarcinoma (2)

Technology Type

Mass Spectrometry (8)
Shotgun proteomics (6)
Illumina HiSeq 2500, ILLUMINA (2)
Mass spectrometry assay (2)
Bottom-up proteomics (2)
Illumina HiSeq 2500, Illumina HiSeq 4000, ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 2000 (1)
Mass spectrometry (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Gel-based experiment (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (3)
Illumina MiSeq (2)
Illumina HiSeq 2000 (2)
DNA 7500 Bioanalyzer Chips (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Orbitrap Fusion (1)
Liquid Chromatography MS - alternating - reverse phase (1)
Liquid Chromatography MS - (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2025 (18)
2014 (18)
2013 (18)
2012 (18)
2010 (18)
2011 (16)
2023 (14)
2015 (14)
2020 (11)
2022 (10)
2024 (9)
2021 (8)
2016 (8)
2008 (7)
2019 (6)
2009 (5)
2026 (5)
2007 (3)
2018 (2)
2017 (2)
2004 (1)

CHEBI ID

CHEBI:167610 (1)
CHEBI:196947 (1)
CHEBI:173633 (1)
CHEBI:77699 (1)
CHEBI:175270 (1)
CHEBI:48946 (1)
CHEBI:191771 (1)
CHEBI:168069 (1)
CHEBI:175514 (1)
CHEBI:74904 (1)
CHEBI:179839 (1)
CHEBI:169438 (1)
CHEBI:31011 (1)
CHEBI:17272 (1)
CHEBI:48944 (1)
CHEBI:17968 (1)
CHEBI:175268 (1)
CHEBI:192169 (1)
CHEBI:156271 (1)
CHEBI:30089 (1)
CHEBI:34711 (1)
CHEBI:165839 (1)
CHEBI:195631 (1)
CHEBI:133508 (1)
CHEBI:4806 (1)
CHEBI:192296 (1)
CHEBI:185330 (1)
CHEBI:178255 (1)
CHEBI:137674 (1)
CHEBI:134281 (1)

Metabolite Name

3-methylvalerate (1)
2-methylbutyrate (1)
Methylphenylsulfide (1)
Isocaproate (1)
9-Methyluric acid (1)
Galloyl glucose (1)
Valerate (1)
3-Methyluric acid (1)
7-Methyluric acid (1)
Isobutyrate (1)
Isovalerate (1)
4-Glucogallic acid (1)
3-Glucogallic acid (1)
2-Methylbenzenethiol (1)
Phenylmethanethiol (1)
Butyric acid (1)
2-Galloylglucose (1)
Gamma-L-Glutamyl-L-pipecolic acid (1)
Acetic acid (1)
1-Methyluric acid (1)
Propionate (1)
Butyrate (1)
Caproic acid (1)
Isobutyric acid (1)
Valeric acid (1)
Propionic acid (1)
Isovaleric acid (1)
Acetate (1)

First Public Date

2023 (22)
2014 (19)
2024 (16)
2025 (13)
2022 (10)
2021 (10)
2026 (8)
2020 (7)
2019 (5)
2018 (3)
2017 (1)
2016 (1)
2015 (1)

Study status

Recruiting (38)
Completed (38)
Terminated (19)
Active, not recruiting (19)
Not provided (5)
Not yet recruiting (3)
Ongoing (2)
Withdrawn (2)
Suspended (1)

Study type

Interventional (115)
Transcription profiling by array (91)
Observational (11)
Comparative genomic hybridization by array (7)
RNA-seq of coding RNA (6)
Unknown experiment type (5)
Proteomic profiling by array (4)
RNA-seq of coding RNA from single cells (3)
ChIP-chip by tiling array (2)
Methylation profiling by array (2)
RNA-seq of non coding RNA (2)
RNA-seq of non coding RNA from single cells (1)
Genotyping by array (1)
RIP-seq (1)
ChIP-seq (1)
DNA-seq (1)
Other (1)

Release Date

2023 (192)
2025 (174)
2022 (159)
2024 (130)
2021 (127)
2020 (119)
2019 (83)
2018 (82)
2016 (79)
2017 (65)
2015 (54)
2014 (51)
2013 (35)
2012 (26)
2011 (26)
2010 (26)
2026 (16)
2008 (7)
2009 (6)
2007 (3)
2004 (2)
2005 (2)
2003 (1)

Lab affiliation

Department of Cellular and Molecular Pharmacology, QUantitative Bioscience Institute, University of California, San Francisco (1)
Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University (1)
Head of Proteomics, Beatson Institute for Cancer Research (1)
Institute of Genetics and Cancer (IGC), University of Edinburgh, Edinburgh, Scotland (1)
MRC Institute of Genetics and Molecular Medicine, Cancer Research UK Edinburgh Centre, The University of Edinburgh ( lab head ) Masaryk Memorial Cancer Institute (1)
REQUIMTE-LAQV, Department of Chemistry and Biochemistry, Faculty of Sciences of the University of Porto, 4169-007 Porto, Portugal (1)
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (1)
i3S - Instituto de Investigacao e Inovacao em Saude, Universidade do Porto, Porto, Portugal. IPATIMUP - Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal. (1)

Location

United States (80)
France (20)
Spain (16)
Japan (15)
Italy (15)
United Kingdom (15)
Belgium (12)
China (11)
Germany (11)
Australia (11)
Canada (9)
Netherlands (9)
South Korea (8)
Taiwan (7)
Poland (7)
Switzerland (4)
Finland (2)
Ireland (2)
India (2)
Turkey (2)
Russia (2)
Israel (2)
Czechia (2)
Austria (2)
Guam (1)
Hong Kong (1)
Norway (1)
Thailand (1)
Denmark (1)
Puerto Rico (1)

Keyword

Pembrolizumab (14)
Fluorouracil (12)
Irinotecan (11)
Leucovorin (9)
Bevacizumab (9)
Oxaliplatin (8)
Nivolumab (7)
Antibodies (7)
Stage IV gastric cancer (6)
Stage IV pancreatic cancer (6)
Stage IV breast cancer (5)
Recurrent gastric cancer (5)
Recurrent pancreatic cancer (5)
Metastatic (5)
Recurrent colon cancer (5)
Stage IV colon cancer (5)
Immunotherapy (5)
Immunoglobulins (5)
Antibodies, Monoclonal (5)
Capecitabine (5)
Cetuximab (5)
Levoleucovorin (5)
Carboplatin (4)
Cyclophosphamide (4)
Cisplatin (4)
Advanced adult primary liver cancer (4)
Recurrent breast cancer (4)
Unresectable gallbladder cancer (4)
Avelumab (4)
Recurrent rectal cancer (4)

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Synergistic Tumor Suppressor Activity of E-cadherin and p53 in a Conditional Mouse Model for Diffuse-Type Gastric Cancer

BACKGROUND & AIMS: Gastric cancer is the second most frequent cause of death from cancer in the world, diffuse-type gastric cancer (DGC) exhibiting a poor prognosis. Germline mutations of CDH1, encoding E-cadherin, have been reported in hereditary DGCs, and genetic and/or epigenetic alterations of C...

ORGANISM(S): Mus musculus

2011-12-04 | E-GEOD-25302 | biostudies-arrayexpress

miRNA signatures of intracellular and extracellular fractions from cancer cell lines

For the purpose of finding a novel tumor marker, we conducted microRNA profiling analysis in fractions of cells, exosomes, and culture medium from seven cancer cell lines. Ranking data of the intracellular and extracellular microRNAs obtained by microarray analysis, we found that let-7 microRNA fami...

ORGANISM(S): Homo sapiens

2010-04-16 | E-GEOD-21350 | biostudies-arrayexpress

Proteomic Profiling of Serum Exosomes from Patients with Metastatic Gastric Cancer

Clinical management of metastatic gastric cancer (mGC) remains a major challenge due to a lack of specific biomarkers and effective therapeutic targets. Recently, accumulating evidence has suggested that exosomes play an essential role in cancer metastasis and can be an excellent reservoir of novel ...

ORGANISM(S): Homo sapiens (Human)

2020-06-29 | PXD019387 | Pride

Transcription profiling of mouse model of Helicobacter-induced gastric cancer

We have previously reported human gastrin overexpressing transgenic mice (=INS-GAS mice) and Helicobacter felis (=H.felis) infection synergistically accelerated gastric cancer in mice stomachs. (Wang et al 2000) Using this mouse model, we employed microarray analysis of gene expression profiling t...

ORGANISM(S): Mus musculus

2008-06-13 | E-GEOD-4651 | biostudies-arrayexpress

Gastric Cancer Study GC_126

126 gastric tissues (90 tumor, 14 lymphnode and 22 normal) assayed using 44K human arrays against common reference (CRG). Published by Leung et al, PNAS, 2002 (PubMed ID 12456890) and Chen et al, MBC, 2003. A clinical history design type is where the organisms clinical history of diagnosis, treatmen...

ORGANISM(S): Homo sapiens

2010-06-10 | E-GEOD-2701 | biostudies-arrayexpress

Identification of pathogenic microRNAs in Helicobacter pylori-associated gastric cancer

To identify dysregulated miRNA(s) upon infection with H. pylori during different pre-malignant and malignant stages of gastric cancer in a mouse model miRNA expression in pre-neoplastic and neoplastic lesions in murine stomachs induced by H. pylori and N-methyl-N-nitrosourea (MNU) after 12 months wa...

ORGANISM(S): Mus musculus

2015-03-04 | E-GEOD-62503 | biostudies-arrayexpress

Clinical response of metastatic gastric cancer patients to cisplatin and fluorouracil (CF) combination chemotherapy

This study was conducted to identify transcriptional profiles predictive of a clinical response of metastatic gastric cancer patients to cisplatin and fluorouracil (CF) combination chemotherapy. Endoscopic biopsy samples were collected from CF-treated metastatic gastric cancer patients prior to ther...

ORGANISM(S): Homo sapiens

2011-06-01 | E-GEOD-14208 | biostudies-arrayexpress

Insulin and the insulin receptor collaborate to promote human gastric cancer.

Not available

S-EPMC8732810 | biostudies-literature

Identification of Multiomics and Immune Infiltration-Associated Biomarkers for Gastric Cancer

Fresh peripheral blood was collected from gastric cancer patients in the second hospital of Lanzhou University. There were 30 patients with non metastatic gastric cancer (GCMN), 29 patients with healthy control group (NC), 31 patients with gastric mucosal lesions (GML), 8 patients with non metastati...

ORGANISM(S): Homo Sapiens

2025-02-21 | PXD061032 |

Pembrolizumab in metastatic gastric cancer

Pembrolizumab in metastatic gastric cancer: comprehensive molecular characterization of clinical response

PRJEB25780 | ENA

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