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GenomicsThe role of H3K36 methylation and associated methyl transferases in chromosome-specific gene regulation
The role of H3K36 methylation and associated methyl transferases in chromosome-specific gene regulation
PRJNA702437 | ENA
TranscriptomicsHP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster
Heterochromatin protein 1 (HP1) proteins are important regulators of heterochromatin mediated gene silencing and chromosome structure and it is well known as the reader of the heterochromatin mark methylation of histone H3 lysine 9 (H3K9me). In Drosophila three different histone lysine methyl transf...
ORGANISM(S): Drosophila melanogaster 
2012-12-21 | E-GEOD-38366 | biostudies-arrayexpress
UnknownHemK, a class of protein methyl transferase with similarity to DNA methyl transferases, methylates polypeptide chain release factors, and hemK knockout induces defects in translational termination.
Not available
S-EPMC122215 | biostudies-literature
Genomics
Functional characterization of plant histone methyl transferases
PRJNA755600 | ENA
ProteomicsMnx1 Induces Leukemia Transformation Through Altering Histone Methylation in a Model of Pediatric t(7;12) Acute Myeloid Leukemia
Acute myeloid leukemia (AML) in children with cytogenetic aberrations like translocation t(7;12)(q36;p13) is associated with inferior outcome. The translocation can lead to a fusion transcript MNX1::ETV6 but also to activation of MNX1 transcription. We generated an AML mouse model by transplantatio...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-30 | PXD034416 | Pride
Aml Mnx1::etv6 Homeodomain T(7 12) Pediatric aml Mnx1 Methyl-transferases 
GenomicsBurkitt Lymphoma beyond MYC translocation:N-MYC and DNA methyl transferases dysregulation
Identification of miRNA differentially expressed between MYC-translocation positive and and MYC-translocation negative Burkitt Lymphoma and their impact on gene expression profile
ORGANISM(S): synthetic construct Homo sapiens 
2015-08-05 | GSE71471 | GEO
GenomicsHomo sapiens
Burkitt Lymphoma beyond MYC translocation:N-MYC and DNA methyl transferases dysregulation
PRJNA291340 | ENA
TranscriptomicsBurkitt Lymphoma beyond MYC translocation:N-MYC and DNA methyl transferases dysregulation
Identification of miRNA differentially expressed between MYC-translocation positive and and MYC-translocation negative Burkitt Lymphoma and their impact on gene expression profile Study of microRNA profile of MYC-translocation positive and MYC-translocation negative Burkitt Lymphoma cases in order t...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-71471 | biostudies-arrayexpress
TranscriptomicsThe role of H3K36 methylation and associated methyl transferases in chromosome-specific gene regulation
In Drosophila, two chromosomes require special mechanisms to balance their transcriptional output to the rest of the genome. These are the male-specific lethal complex targeting the male X chromosome and Painting of fourth targeting chromosome 4. Here, we explore the role of histone H3 methylated at...
ORGANISM(S): Drosophila melanogaster 
2021-08-10 | GSE166934 | GEO
GenomicsSpecific phosphorylation of histone demethylase KDM3A determines target gene expression in response to heat shock
Histone lysine (K) residues, which are modified by methyl- and acetyl-transferases, diversely regulate RNA synthesis. Unlike the ubiquitously activating effect of histone K acetylation, the effects of histone K methylation vary with the number of methyl groups added and with the position of these gr...
ORGANISM(S): Homo sapiens 
2014-10-15 | E-GEOD-62309 | biostudies-arrayexpress
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