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ProteomicsSite-selective photo crosslink to methyllysine readers via single electron transfer between sulfonium and tryptophan
Reader proteins play significant roles in cell signaling from site-specific lysine methylation, but the progress of new reader investigations is rather slow. Photoreactive crosslinkers enable reader identifications, but it requires laborious chemical synthesis for optimization of the photoreactive g...
ORGANISM(S): Homo Sapiens 
2024-02-04 | PXD049149 |
UnknownRegulation of Methyllysine Readers through Phosphorylation.
Not available
S-EPMC4861070 | biostudies-literature
ProteomicsSingle electron transfer between sulfonium and tryptophan enables site-selective photo crosslinking of methyllysine reader proteins
Reader proteins play significant roles in cell signaling from site-specific lysine methylation, but progress of new reader investigations is rather slow. Photoreactive crosslinkers enable the discovery of reader proteins, but the chemical synthesis required to optimize the placement of the photorea...
ORGANISM(S): Homo sapiens (Human) 
2024-06-30 | PXD051693 | Pride
Methyllysine readers Sulfonium Tryptophan Photo crosslinking 
UnknownEngineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
Not available
S-EPMC6988089 | biostudies-literature
UnknownSearching for methyllysine-binding aromatic cages.
Not available
S-EPMC9416871 | biostudies-literature
UnknownDevelopment of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins.
Not available
S-EPMC12904088 | biostudies-literature
UnknownTowards understanding methyllysine readout.
Not available
S-EPMC4453862 | biostudies-literature
Methylation profilingDNA methylation analysis of HCT116 after disruption of methyllysine reading and writing.
The chromatin-binding E3 ubiquitin ligase Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) maintains DNA methylation patterning in cancer cells through multivalent histone and DNA recognition. The tandem Tudor domain (TTD) of UHRF1 is well-characterized as a reader of lysine 9 di- and tri-m...
ORGANISM(S): Homo sapiens 
2020-04-05 | GSE148086 | GEO
GenomicsDNA methylation analysis of HCT116 after disruption of methyllysine reading and writing.
DNA methylation analysis of HCT116 after disruption of methyllysine reading and writing.
PRJNA623121 | ENA
UnknownSelective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family.
Not available
S-EPMC4753544 | biostudies-literature
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