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MetabolomicsDecreasing peptide deformylase activity is a beneficial strategy for increasing formaldehyde resistance in Methylobacterium extorquens
Formaldehyde is a highly toxic metabolite that can cause extensive damage to DNA and proteins, and strategies to mitigate formaldehyde toxicity are poorly understood. Methylotrophic bacteria, such as Methylobacterium extorquens, thrive on one-carbon compounds as sole sources of carbon and energy. Th...
2026-10-05 | MTBLS15927 | MetaboLights
TranscriptomicsEthylamine versus succinate cells of Methylobacterium extorquens
In order to provide global information on gene expression during growth on C2 compounds, microarray analysis of M. extorquens AM1 cells was carried out, comparing ethylamine-grown cells to succinate-grown cells. This comparison has confirmed previous observations on the inducible nature of some of t...
ORGANISM(S): Methylobacterium extorquens 
2010-05-14 | E-GEOD-20365 | biostudies-arrayexpress
ProteomicsDifferential analysis of Methylobacterium extorquens DM4 in methanol versus dichloromethane condition
Differential analysis of Methylobacterium extorquens DM4 in methanol versus dichloromethane condition using shotgun label free MS1 quantification approach
ORGANISM(S): Methylobacterium extorquens DM4 
2018-04-25 | PXD006838 | Pride
Differential analysis of methylobacterium extorquens dm4 
ProteomicsUse of rare-earth elements in the phyllosphere colonizer Methylobacterium extorquens PA1
Until recently, rare-earth elements (REEs) had been thought to be biologically inactive. This view changed with the discovery of the methanol dehydrogenase (Mdh) XoxF that strictly relies on REEs for its activity. Some methylotrophs only contain xoxF, while others, including the model phyllosphere c...
ORGANISM(S): Methylobacterium extorquens PA1 
2019-01-21 | PXD011842 | Pride
Rare earth metals Arabidopsis Methanol Ion transport Proteomics Methylobacterium extorquens 
TranscriptomicsFormaldehyde stress response in Methylobacterium extorquens AM1
The goal of this study was to use microarrays to identify genes differentially regulated under conditions of formaldehyde stress relative to two other stress conditions (oxidative, osmotic) in an effort to identify genes that might be involved in a formaldehyde-specific stress response, rather than ...
ORGANISM(S): Methylobacterium extorquens AM1 
2015-01-01 | E-GEOD-15631 | biostudies-arrayexpress
TranscriptomicsTransition from succinate to methanol growth in Methylobacterium Extorquens AM1
In order to provide information about the gene expression response that occurs when cells experience a change in carbon source, succinate limited chemostat cultures of Methylobacterium extorquens AM1 were grown to and maintained at an OD of ~0.63, transferred to flasks and methanol was added. Cells...
ORGANISM(S): Methylobacterium extorquens AM1 
2011-07-31 | E-GEOD-22031 | biostudies-arrayexpress
ProteomicsMethylobacterium extorquens AM1 on methanol
Methylobacterium extorquens AM1 on methanol
ORGANISM(S): Methylobacterium extorquens group 
2012-02-28 | PRD000446 | Pride
ProteomicsMethylobacterium extorquens AM1 on acetate
Methylobacterium extorquens AM1 on acetate
ORGANISM(S): Methylobacterium extorquens group 
2012-02-28 | PRD000445 | Pride
TranscriptomicsFast Growth Increases the Selective Advantage of a Mutation Arising Recurrently during Evolution under Metal Limitation
The goal was to use microarray to compare changes in the global transcription profiles between an engineered bacterial strain and one of its descendants subject to 600 generations of experimental evolution in batch culture. This comparison allowed us to identify a beneficial mutation that substantia...
ORGANISM(S): Methylobacterium extorquens AM1 
2010-06-20 | E-GEOD-14875 | biostudies-arrayexpress
ProteomicsProteogenomic analysis of Mehtylobacterium extorquens DM4
Proteogenomic analysis of Methylobacterium extorquens DM4 using the dN-TOP strategy with heavy and light TMPP labelling
ORGANISM(S): Methylobacterium extorquens DM4 
2018-04-25 | PXD006836 | Pride
N terminome analysis - dn-top strategy 
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