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ProteomicsHsp90-downregulation influences the heat-shock response, innate immune response and onset of oocyte development in nematodes.
Hsp90 is a molecular chaperone involved in the regulation and maturation of kinases and transcription factors. In C. elegans Hsp90 participates in the development of fertility, maintenance of muscle structure and the regulation of stress response and dauer state. To understand the consequences of Hs...
ORGANISM(S): Caenorhabditis elegans 
2018-10-17 | PXD006185 | Pride
Hsp90 Immune system Lc/ms Nematodes 
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
TranscriptomicsTranscription profiling of femoral fracture healing in Rattus norvegicus subjects comparing intramedullary nailing, screw and plate fixation, and sham surgery
This is a study of femoral fracture healing in female rats 16 weeks old at fracture to compare intramedullary nailing, screw and plate fixation, and sham surgery. The sham surgery group received a surgical exposure of the femur, but no fracture, no plate, and no nail. Samples were collected at 1 d...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-1685 | biostudies-arrayexpress
ProteomicsDevelopmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium
The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic development in metazoans. However, it is currently unknown whether a similar process exists in unicellular eukaryotes. The ciliate Paramecium tetraurelia harbors a vast array of Argonaute proteins of the Piwi-clade ...
ORGANISM(S): Paramecium tetraurelia 
2023-05-10 | PXD038984 | Pride
Paramecium tetraurelia Piwi Mrna clearance Untranslated mrna Total protein < 25kda Sirnas 
UnknownEffect of ocular hypertension on the pattern of retinal ganglion cell subtype loss in a mouse model of early-onset glaucoma.
Not available
S-EPMC7430001 | biostudies-literature
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
UnknownComparison of traditional field retting and Phlebia radiata Cel 26 retting of hemp fibres for fibre-reinforced composites.
Not available
S-EPMC5342995 | biostudies-literature
TranscriptomicsAnalysis of splicing changes in motoneurons from mice of a severe model for Spinal Muscular Atrophy (SMA)
Motoneuron cell bodies were isolated by laser capture microdissection from severe SMA mice at postnatal day 3. The comparison was between heterozygote carriers, SMA disease mice and SMA mice rescued by a U7 snRNA correcting the splicing of human SMN2.
ORGANISM(S): Mus musculus 
2015-03-05 | E-MTAB-3170 | biostudies-arrayexpress
UnknownAssociation between Fatty Acid Composition in Hair and Energy Availability during Early Lactation in Simmental and German Holstein Cows.
Not available
S-EPMC9781642 | biostudies-literature
TranscriptomicsMYC regulation of a "poor prognosis" metastatic cancer cell state
This SuperSeries is composed of the following subset Series: GSE14987: Expression data from ERBB2 over-expression and EGF stimulation in MCF10A cells GSE14988: Expression data from DHT stimulation vs. control in LNCaP cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-14990 | biostudies-arrayexpress
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