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UnknownThe EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome.
Not available
S-EPMC10132433 | biostudies-literature
UnknownRibonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models.
Not available
S-EPMC9533739 | biostudies-literature
ProteomicsQuantitative proteomic approach identifies Vpr binding protein as novel host factor supporting influenza A virus infections in human cells
Influenza A virus infections are a major cause for respiratory disease in humans, which affects all age groups and contributes substantially to global morbidity and mortality. IAV have a large natural host reservoir in avian species. However, many avian IAV strains lack adaptation to other hosts and...
ORGANISM(S): Homo sapiens (Human) 
2017-03-14 | PXD005825 | Pride
Influenza Quantitative proteomics Vprbp 
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
UnknownDevelopment of the reproduction number from coronavirus SARS-CoV-2 case data in Germany and implications for political measures.
Not available
S-EPMC7840427 | biostudies-literature
UnknownNovel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias.
Not available
S-EPMC9208280 | biostudies-literature
ProteomicsMutations in disordered regions cause disease by creating dileucine motifs - BioID
Many disease-causing missense mutations affect intrinsically disordered regions (IDRs) of proteins. Since these mutations do not affect protein structure, the molecular mechanism of their pathogenicity is enigmatic. Here, we employ a peptide-based proteomic screen to investigate the impact of mutati...
ORGANISM(S): Homo sapiens (Human) 
2018-09-13 | PXD010061 | Pride
Bioid Proximity labeling 
ProteomicsMutations in disordered regions cause disease by creating dileucine motifs - peptide-protein interaction screen
Many disease-causing missense mutations affect intrinsically disordered regions (IDRs) of proteins. Since these mutations do not affect protein structure, the molecular mechanism of their pathogenicity is enigmatic. Here, we employ a peptide-based proteomic screen to investigate the impact of mutati...
ORGANISM(S): Homo sapiens (Human) 
2018-09-13 | PXD010027 | Pride
Peptide array Ppi Protein-protein interaction Disordered regions 
UnknownSimplified Bioprinting-Based 3D Cell Culture Infection Models for Virus Detection.
Not available
S-EPMC7698278 | biostudies-literature
TranscriptomicsCanine Cutaneous Peripheral Nerve Sheath Tumours versus Fibrosarcomas can be Differentiated by Neuroectodermal Marker Genes in their Transcriptome.
The diagnostic differentiation of canine fibrosarcomas and peripheral nerve sheath tumors (PNST) is mainly based on their histopathologic phenotype. Histologic differentiation of these tumors can, however, be difficult and there is a lack of immunohistochemical markers to prove their histogenic orig...
ORGANISM(S): Canis lupus familiaris 
2012-10-30 | E-GEOD-34382 | biostudies-arrayexpress
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