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UnknownNKG2A-checkpoint inhibition and its blockade critically depends on peptides presented by its ligand HLA-E.
Not available
S-EPMC9426624 | biostudies-literature
TranscriptomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin, and several studies postulated a role for cyclin C in driving cell proliferation. Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcriptional ...
ORGANISM(S): Mus musculus 
2014-09-02 | E-GEOD-58712 | biostudies-arrayexpress
UnknownEffects of dexmedetomidine on oxygenation during one-lung ventilation for thoracic surgery in adults.
Not available
S-EPMC3193692 | biostudies-literature
Proteomics,MultiomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
TranscriptomicsRNA-seq of Oligotropha carboxidovorans strain OM5, a promising candidate for the aerobic utilization of synthesis gas, heterotrophically (acetate) and autotrophically (syngas) grown.
Oligotropha carboxidovorans strain OM5 is an aerobic carboxidotrophic bacterium and potentially a promising candidate for such processes. We here performed RNA-Seq analysis comparing cells of this organism grown heterotrophically with acetate or autotrophically with CO2, CO and H2 as carbon and ener...
ORGANISM(S): Oligotropha carboxidovorans OM5 
2020-02-21 | E-MTAB-8786 | biostudies-arrayexpress
TranscriptomicsDetecting lung tumors from circulating microRNA profiles
We aimed to determine if lung cancer detection can be improved by circulating miRNAs as biomarkers. To this end, we collected blood of over 3000 individuals using PAXgene blood tubes. The individuals were diagnosed with lung cancer (LCa), a non-tumor lung disease (NTLD), another disease (OD) or were...
ORGANISM(S): Homo sapiens 
2020-05-19 | E-MTAB-8026 | biostudies-arrayexpress
UnknownPeripheral Blood Gene Expression Changes Associated With Primary Graft Dysfunction After Lung Transplantation.
Not available
S-EPMC5489369 | biostudies-literature
TranscriptomicsSpatio-temporal transcriptome of the human brain
The development of the human brain is a complex and precisely regulated process that unfolds over a protracted period of time. Human-specific features of this process, especially the ways in which highly complex neural circuits of the cerebral cortex form, are likely to be important factors in the e...
ORGANISM(S): Homo sapiens 
2011-10-26 | E-GEOD-25219 | biostudies-arrayexpress
GenomicsInternational Multi-Center ADHD Gene Project (IMAGE) II Case Sample

This sample represents a collection of cases across a range of sites. All of these samples were ascertained for ADHD with most meeting criteria for combined type ADHD. The collection sites span Europe and America. Further details on the source and inclusion and exclusion information can be found ...

phs000407.v1.p1 | EGA
GenomicsSpatiotemporal Transcriptome of the Human Brain

Comprehensive knowledge about the spatiotemporal dynamics of the brain transcriptome is essential for a better understanding of neurodevelopment, sexual dimorphism, and evolution, as well as our increased susceptibility to certain brain disorders. We generated and analyzed genome-wide exo...

phs000406.v1.p1 | EGA
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