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ProteomicsMHCI peptidome of HepG2 with ArgRS or SRRM2 knock down
Cells need to sense and respond adequately to environmental stimuli. Metabolites provide information on systemic changes, for example during inflammation. We show that depletion of the amino acid arginine during inflammation reduced nuclear levels of its cognate aminoacyl tRNA synthetase, Arginyl-tR...
ORGANISM(S): Homo sapiens (Human) 
2025-06-12 | PXD027531 | Pride
Inflammation Mhci Mrna splicing 
ProteomicsMHCI peptidome of HepG2 with ArgRS or SRRM2 knock down
Cells respond to perturbations like inflammation by sensing changes in metabolite levels. Especially prominent is arginine, which has known connections to the inflammatory response. Here, we found that depletion of arginine during inflammation decreased levels of a nuclear form of arginyl-tRNA synth...
ORGANISM(S): Homo sapiens (Human) 
2023-04-14 | PXD036232 | Pride
Inflammation Mhci Peptidome 
GenomicsBovine MHCI haplotypes
Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations Using Next-Generation Sequencing
PRJEB14552 | ENA
TranscriptomicsDistinguishing innate memory CD8+ T from homeostatically expanded CD8+ T cells
Innate memory phenotype (IMP) CD8+ T cells are non-conventional αβ T cells exhibiting features of innate immune cells, and are significantly increased in the absence of non-receptor tyrosine kinase ITK. Their developmental path and function are not clear, particularly whether they can contribute to ...
ORGANISM(S): Mus musculus 
2013-02-19 | E-GEOD-41482 | biostudies-arrayexpress
UnknownHigh-throughput identification of conditional MHCI ligands and scaled-up production of conditional MHCI complexes.
Not available
S-EPMC8138534 | biostudies-literature
GenomicsBos taurus
Bovine MHCI haplotypes
PRJNA326389 | ENA
UnknownCryptic protein-protein interaction motifs in the cytoplasmic domain of MHCI proteins.
Not available
S-EPMC4950430 | biostudies-literature
Genomics
eORFeome MHCI screen
PRJNA1481684 | ENA
UnknownMHCI negatively regulates synapse density during the establishment of cortical connections.
Not available
S-EPMC3251641 | biostudies-literature
UnknownViral MHCI inhibition evades tissue-resident memory T cell formation and responses.
Not available
S-EPMC6314518 | biostudies-literature
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