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TranscriptomicsBlood Leukocyte Microarrays to Diagnose Systemic Onset Juvenile Idiopathic Arthritis and Follow IL-1 blocade
Systemic onset Juvenile Idiopathic Arthritis (SoJIA) represents up to 20% of Juvenile Idiopathic Arthritis (JIA). We have previously reported that this disease is Interleukin 1 (IL1)-mediated, and that IL-1 blockade results in clinical remission in the majority of patients. The diagnosis of SoJIA, h...
ORGANISM(S): Homo sapiens 
2007-09-01 | E-GEOD-8650 | biostudies-arrayexpress
UnknownSustained hippocampal neuroinflammation and subsequent glutamatergic dysfunction in juvenile idiopathic arthritis: evidence from proton magnetic resonance spectroscopy (<sup>1</sup>H-MRS).
Not available
S-EPMC12754929 | biostudies-literature
ProteomicsMouse Kidney TMT Quantitative Proteomics
We extracted proximal renal tubules of WT and Lonp1-cKO mice (n=3), and then performed isobaric tags for relative and absolute quantification (iTRAQ)-based quantitative proteomic analysis to assess differential protein-expression levels.
ORGANISM(S): Mus musculus (Mouse) 
2022-12-09 | PXD037552 | Pride
Lc-ms/ms Mouse Kidney 
ProteomicsQuantitative proteomic analysis of keloid scars and normal skin tissues
Keloid scars is a pathologic fibro-proliferative disorders of the skin, which exhibit abnormal phenotypes including fibroblasts proliferation and collagen deposits. There have been several treatments of keloids including conventional surgical therapies and adjuvant therapies, but a high recurrence r...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD029631 | Pride
Keloids Proteomics Endoplasmic reticulum Lc-ms/ms， Bioinformatics 
UnknownEvolutionary history and pan-genome dynamics of strawberry (Fragaria spp.).
Not available
S-EPMC8609306 | biostudies-literature
UnknownA Phase II Dose-Ranging Study Evaluating the Efficacy and Safety of the Orexin Receptor Antagonist Filorexant (MK-6096) in Patients with Primary Insomnia.
Not available
S-EPMC5006195 | biostudies-literature
ProteomicsQuantitative Proteomics analysis of Prostate Cancer Mice Model
The entire prostates from transgenetic mice and normal mice were quantitatively analysis with MS-based Label free proteomics approach.
ORGANISM(S): Mus musculus (Mouse) 
2018-06-26 | PXD003749 | Pride
Mouse Prostate Prostate cancer 
UnknownMERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.
Not available
S-EPMC4624558 | biostudies-literature
MetabolomicsAnti-anemia drug FG4592 retards the AKI to CKD transition by improving vascular regeneration and anti-oxidative capability (day 21)

Acute kidney injury (AKI) is a known risk factor for the development of chronic kidney disease (CKD), with no satisfactory strategy to prevent the progression of AKI to CKD. Damage to the renal vascular system and subsequent hypoxia are common contributors to both AKI and CKD. Hypoxia inducible f...

2021-07-22 | MTBLS3003 | MetaboLights
ProteomicsThe NuRD complex is required for Thpok-mediated CD4+ T cell development
This data represent characterization of the interactome of murine Thpok. A version of Thpok (Thpok-Bio) subject to biotinylation in vivo by the BirA biotin ligase was used; to assess Thpok interactions in primary cells, Thpok-Bio was retrovirally expressed in in vitro activated CD4+ T cells from Thp...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000088126 | MassIVE
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