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UnknownA near telomere-to-telomere genome assembly of the Jinhua pig: enabling more accurate genetic research.

Background

Pigs are crucial sources of meat and protein, valuable animal models, and potential donors for xenotransplantation. However, the existing reference genome for pigs is incomplete, with thousands of segments and centromeres and telomeres missing, which limits our understanding of th...
S-EPMC12080228 | biostudies-literature
UnknownTranscriptome analysis reveals differential gene expression in intramuscular adipose tissues of Jinhua and Landrace pigs.
Meat is a rich source of protein, fatty acids and carbohydrates for human needs. In addition to necessary nutrients, high fat contents in pork increase the tenderness and juiciness of the meat, featuring diverse application in various dishes. This study investigated the transcriptomic profiles of in...
S-EPMC6021883 | biostudies-literature
UnknownImproper handling of vomitus as a risk factor in the human norovirus outbreak in a kindergarten in Wuyi County, Zhejiang Province, China.
This study investigated an outbreak in a kindergarten in Wuyi County of acute gastroenteritis concerning a large number of students and teachers. We performed a case-control study, and collected information on the layout of the school, symptoms, onset time of all cases and vomiting sites. A total of...
S-EPMC9214846 | biostudies-literature
UnknownSerum Syndecan-1 levels in patients with immunoglobulin A vasculitis in children.

Objective

The aim of this study was to evaluate the serum Syndecan-1 (SDC-1) levels in patients with immunoglobulin-A vasculitis (IgAV) in children and its relation with gastrointestinal involvements.

Methods

Sixty-eight children with IgAV and 48 healthy children were enrolled in this...
S-EPMC9510791 | biostudies-literature
UnknownThe Plant Volatile-Sensing Mechanism of Insects and Its Utilization.
Plants and insects are engaged in a tight relationship, with phytophagous insects often utilizing volatile organic substances released by host plants to find food and egg-laying sites. Using plant volatiles as attractants for integrated pest management is vital due to its high efficacy and low envir...
S-EPMC10819770 | biostudies-literature
UnknownInvestigating potential drug targets for IgA nephropathy and membranous nephropathy through multi-queue plasma protein analysis: a Mendelian randomization study based on SMR and co-localization analysis.

Background

Membranous nephropathy (MN) and IgA nephropathy (IgAN) pose challenges in clinical treatment with existing therapies primarily focusing on symptom relief and often yielding unsatisfactory outcomes. The search for novel drug targets remains crucial to address the shortcomings in ma...
S-EPMC11545554 | biostudies-literature
UnknownIdentification of the <i>Populus euphratica XTHs</i> Gene Family and the Response of <i>PeXTH7</i> to Abiotic Stress.
Populus euphratica Oliv. serves as a keystone species in desert riparian ecosystems. Owing to its pronounced tolerance to drought and salinity, as well as its robust reproductive capacity, it has become a pioneer species in desert oases. The xyloglucan endotransglucosylase (XET)/hydrolase (
S-EPMC12737017 | biostudies-literature
UnknownGenome-Wide Identification of the <i>SnRK2</i> Gene Family and Its Response to Abiotic Stress in <i>Populus euphratica</i>.
Improving plant water use efficiency (WUE) and drought tolerance by modulating stomatal activity constitutes a promising strategy for mitigating the impacts of water scarcity. SnRK2, a key component of the abscisic acid (ABA) signaling pathway, plays a critical role in modulating stomatal beh...
S-EPMC12608763 | biostudies-literature
UnknownCharacterisation of the <i>ARF</i> Gene Family in Salicaceae and Functional Analysis of <i>PeARF18</i> in Heteromorphic Leaf Development of <i>Populus euphratica</i>.
Auxin plays a crucial role in plant growth and development via concentration gradient regulation, with auxin response factors (ARFs) as key transcription factors in its signalling pathway. However, comprehensive identification and characterisation of ARF genes in Salicaceae remain limited. Th...
S-EPMC12785610 | biostudies-literature
UnknownIGFBP2 from a novel copper metabolism-associated biomarker promoted glioma progression and response to immunotherapy.

Introduction

Copper metabolism encompasses all cellular metabolic processes involving copper ions and plays a significant role in the pathogenesis of diseases, including cancer. Furthermore, copper is intricately involved in various processes related to nucleotide metabolism. However, a comp...
S-EPMC10620745 | biostudies-literature
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