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TranscriptomicsAccumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae
To investigate the possible range of additional RNase P substrates in vivo a strand-specific, high-density microarray was used to analyze what RNA accumulates with a mutation in the catalytic RNA subunit of nuclear RNase P in Saccharomyces cerevisiae. A wide variety of noncoding RNAs were shown to a...
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-29 | E-MEXP-3140 | biostudies-arrayexpress
ProteomicsDiscerning strain specific beta-lactam drug resistance of P. aeruginosa
P. aeruginosa isolates were grown in LB broth media. The bacterial media was then digested after incubation for 24 hours and analyzed to identify bacterial proteins related to beta-lactam drug resistance. Bottom-up proteomics analysis was performed.
ORGANISM(S): Pseudomonas aeruginosa 
2018-11-04 | PXD010588 | Pride
P. aruginosa Drug resistance Bacteria 
Unknownc-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies
Not available
S-JCBD-201006089 | bioimages
UnknownHepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats.
Not available
S-EPMC5364093 | biostudies-literature
TranscriptomicsA compendium of antibiotic-induced transcription profiles reveals broad regulation of P. multocida virulence genes
Treatment of bacteria with antibiotics at or close to the inhibitory concentration leads to specific transcriptional responses often affecting target genes and targets pathways. A dataset of transcriptional profiles (compendium) induced by antibiotics with known mode-of-action (MoA) can be used to g...
ORGANISM(S): Pasteurella multocida 
2008-06-01 | E-GEOD-10051 | biostudies-arrayexpress
UnknownThe Phospha-Michael addition product {(t-BuNH)P(μ-N-t-Bu)(2)P(=N-t-Bu)-C(=CH(2))CH(p-CH(3)O-C(6)H(4))-P(O)[(OCH(2)C(CH(3))(2)CH(2)O)]}.
Not available
S-EPMC3089203 | biostudies-literature
Proteomics(Phospho)-proteomic characterization of longitudinal biopsies from HCC patients treated with sorafenib
Tumor response rates to targeted therapy are generally low. This poses an urgent medical need to identify molecular mechanisms that determine responsiveness, to inform drug development and therapy. Here, we performed a proteomics and phospho-proteomics (p)proteomics analysis on longitudinal tumor bi...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD028593 | Pride
Human Super-silac Sorafenib (phospho)-proteomics ((p)proteomics) Hepatocellular carcinoma (hcc) Biopsies 
TranscriptomicsSingle-cell RNA sequencing of a 3D blood-brain-barrier model perfused with P. falciparum-infected red blood cells and egress products
This dataset consists of two individual sample-multiplexing (MULTI-seq) single-cell RNA sequencing experiments, MB10x01 and MB10x02. Single-cell RNA sequencing (10X Genomics) analyses were performed on a microfluidic 3D in vitro blood-brain-barrier model (containing primary human brain microvascular...
ORGANISM(S): Homo sapiens 
2025-06-25 | E-MTAB-14463 | biostudies-arrayexpress
TranscriptomicsC.elegans exposed to P. aeurigonsa: Colonized vs Non colonized animals
Transcriptional profiling of adult C.elegans exposed to E.coli or to GFP-expressing P. aeruginosa (strain PA14). For P. aeruginosa exposure, worms were separated into 2 groups - fully colonized (green) or non-colonized (dark). Three conditions (E.coli, P. aeurginosa colonized, and P. aeurginosa non-...
ORGANISM(S): Caenorhabditis elegans 
2012-07-19 | E-GEOD-39536 | biostudies-arrayexpress
TranscriptomicsTranscriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen
Characterization of bacterial behavior in the microgravity environment of spaceflight is of importance towards risk assessment and prevention of infectious disease during long-term missions. Further, this research field unveils new insights into connections between low fluid-shear regions encountere...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2011-06-28 | E-GEOD-22684 | biostudies-arrayexpress
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