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ProteomicsHEK293T Coa6 knockout mitochondria
Biogenesis of complex IV of the mitochondrial respiratory chain requires assembly factors for subunit maturation, co-factor attachment and stabilization of intermediate assemblies. A pathogenic mutation in Coa6, leading to substitution of a conserved tryptophan to a cysteine residue, results in a lo...
ORGANISM(S): Homo sapiens (Human) 
2016-07-28 | PXD001958 | Pride
Human Mitochondria Hek293t 
Proteomics5HT - Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
we provide evidence for a new class of histone posttranslational modification (PTM): serotonylation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-04 | MSV000093567 | MassIVE
MetabolomicsAmphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism, lipid transport and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed tha...

2022-09-22 | MTBLS2744 | MetaboLights
TranscriptomicsTranscription profiling of human peripheral blood monocytes in periodontal therapy
Periodontal infections have been associated with systemic inflammation and risk for atherosclerosis and vascular disease. We investigated the effects of comprehensive periodontal therapy on gene expression of peripheral blood monocytes. Approximately 1/3 of the patients showed substantial changes in...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6751 | biostudies-arrayexpress
UnknownReducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries.
Not available
S-EPMC10364528 | biostudies-literature
UnknownPredominantly Persistent Intraretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials.
Not available
S-EPMC10282893 | biostudies-literature
GenomicsNational Cancer Institute Genome-Wide Association Study of Renal Cell Carcinoma

The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-con...

phs000351.v1.p1 | EGA
UnknownDesigning a broad-spectrum integrative approach for cancer prevention and treatment.
Not available
S-EPMC4819002 | biostudies-literature
UnknownA Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.
Not available
S-EPMC5959730 | biostudies-literature
UnknownSubretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials.
Not available
S-EPMC4549177 | biostudies-literature
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