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MetabolomicsMicrobial metabolites calibrate innate immunity upon systemic viral infection

Gut microbiome dysbiosis is often associated with immune-mediated diseases. Here, we used germ-free (GF) mice, the synthetic minimal consortium OMM12, and specific pathogen-free (SPF) mice to dissect the causal influence of the microbiome on anti-viral immunity. The lack of microbial diversity af...

2026-08-01 | MTBLS7382 | MetaboLights
MetabolomicsSponges With Microbial Symbionts Transform Dissolved Organic Matter and Take Up Organohalides (2018 collection assay)

Seawater dissolved organic matter (DOM) is a large reservoir of carbon composed of a complex and poorly characterized mixture of molecules. Sponges have long been known to consume dissolved organic carbon (DOC) from this mixture, but the role of microbial sponge symbionts in this process is compl...

2022-03-11 | MTBLS2199 | MetaboLights
MetabolomicsSponges With Microbial Symbionts Transform Dissolved Organic Matter and Take Up Organohalides (2019 collection assay)

Seawater dissolved organic matter (DOM) is a large reservoir of carbon composed of a complex and poorly characterized mixture of molecules. Sponges have long been known to consume dissolved organic carbon (DOC) from this mixture, but the role of microbial sponge symbionts in this process is compl...

2022-03-11 | MTBLS2200 | MetaboLights
MetabolomicsInhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control - LC-MS/MS data

The global type 2 diabetes epidemic is a major health crisis and there is a critical need for innovative strategies to fight it. Although the microbiome plays important roles in the onset of insulin resistance (IR) and low-grade inflammation, the microbial compounds regulating these phenomena rem...

2025-10-20 | MTBLS12975 | MetaboLights
TranscriptomicsA role for programmed cell death in the microbial loop
The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrel...
ORGANISM(S): Halobacterium sp. NRC-1 
2013-05-08 | E-GEOD-45752 | biostudies-arrayexpress
TranscriptomicsA role for programmed cell death in the microbial loop
The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrel...
ORGANISM(S): Halobacterium salinarum NRC-1 
2013-05-08 | GSE45752 | GEO
ProteomicsA metaproteomic analysis of the response of a freshwater microbial community under nutrient enrichment
Eutrophication can lead to an uncontrollable increase in algal biomass, which has repercussions for the entire microbial and pelagic community. Studies have shown how nutrient enrichment affects microbial species succession, however details regarding the impact on community functionality are rare. H...
ORGANISM(S): mixed sample 
2016-08-01 | PXD004592 | Pride
Eutrophic Lc-msms Freshwater Oligotrophic Microbial loop Metaproteomics 
ProteomicsFermentative Spirochaetes drive nutrient cycling by a subsurface microbial loop in hydrocarbon-contaminated habitats
Members of the bacterial phylum Spirochaetes are primarily studied for their commensal and pathogenic roles in animal hosts. However, Spirochaetes are also frequently detected in anoxic hydrocarbon-contaminated environments but their ecological role in such ecosystems has so far remained unclear. He...
ORGANISM(S): uncultured Desulfobacterium sp. Treponema 
2018-05-17 | PXD005624 | Pride
Rectinema cohabitans Desulfobacterium naphthalenivorans Label free quantification ms 
ProteomicsOR Pilot - MBARI OR Algae - Proteins from marine microbial community were extracted, trypsine digested and identified with LC-MS/MS analysis.
Proteins from marine microbial community were extracted, trypsine digested and identified with LC-MS/MS analysis.
ORGANISM(S): uncultured marine microorganism 
2015-08-03 | PXD002641 | Pride
Proteomic sip Marine microbial community Lc-ms/ms 
GenomicsAge associated differences in microbiome in Rhesus Macaque
Aging is associated with declining immunity and inflammation as well as alterations in the gut microbiome with a decrease of beneficial microbes and increase in pathogenic ones. The aim of this study was to investigate aging associated gut microbiome in relation to immunologic and metabolic profile ...
ORGANISM(S): gut metagenome 
2022-02-01 | E-MTAB-10160 | biostudies-arrayexpress
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