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MetabolomicsChemotaxis shapes the microscale organization of the ocean’s microbiome

The capacity of planktonic marine microorganisms to actively seek out and exploit microscale chemical hotspots has been widely theorized to affect ocean-basin scale biogeochemistry, but has never been examined comprehensively in situ among natural microbial communities. Here, using a field-based ...

2022-02-15 | MTBLS1980 | MetaboLights
ProteomicsAn Optimized Miniaturized Filter Aided Sample Preparation Method for Sensitive Cross-linking Mass Spectrometry Analysis of Microscale Samples
Cross-linking mass spectrometry (XL-MS) is a powerful tool for elucidating protein structures and protein-protein interactions (PPIs) at the global scale. However, sensitive XL-MS analysis of mass-limited samples remains challenging, due to serious sample loss during sample preparation of the low-ab...
ORGANISM(S): Homo sapiens (Human) 
2025-01-03 | PXD051322 | Pride
Cross-linking mass spectrometry Microscale samples 
UnknownSensitive Determination of Proteolytic Proteoforms in Limited Microscale Proteome Samples.
Not available
S-EPMC6823850 | biostudies-literature
ProteomicsData for manuscript, “An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples”
Clinical BALF samples are rich in biomolecules, including proteins, and useful for molecular studies of lung health and disease. However, MS based proteomic analysis of BALF is impeded by the dynamic range of protein abundance, and potential for interfering contaminants. We have developed a workflow...
ORGANISM(S): Homo sapiens (Human) 
2023-04-05 | PXD038522 | Pride
Bronchoalveolar lavage fluid  balf  quantitative proteomics  mass spectrometry  sample preparation  lung disease 
ProteomicsSensitive determination of proteolytic proteoforms in limited microscale proteome samples-Development of High-efficiency Undecanal-based N Termini EnRichment (HUNTER)
Protein N-termini reveal fundamental regulatory mechanisms and their perturbation in disease. We present a robust, sensitive, scalable and automatable method called High-efficiency Undecanal-based N Termini EnRichment (HUNTER) for system-wide identification of thousands of N-termini from minute samp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-02-28 | MSV000083501 | MassIVE
GenomicsSalinispora spp.
Microscale Salinispora spp. Project
PRJNA1186208 | ENA
UnknownSpatially resolved measurements of ballistic and total transmission in microscale tissue samples from 450 nm to 1624 nm.
Not available
S-EPMC8803029 | biostudies-literature
UnknownMiniaturized Microscale Solid-Phase Extraction-Based Module for Highly Efficient DNA Extraction and Purification from Grapevine Samples.
Not available
S-EPMC10483517 | biostudies-literature
UnknownpH-FISH: coupled microscale analysis of microbial identity and acid-base metabolism in complex biofilm samples.
Not available
S-EPMC11662800 | biostudies-literature
UnknownSocial interactions and distribution of Bacillus subtilis pherotypes at microscale.
Not available
S-EPMC2648371 | biostudies-literature
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