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ProteomicsAnalysis of the midbody interactome reveals new roles for PP1 phosphatases in late cytokinesis
The midbody is an organelle assembled at the intercellular bridge connecting the two daughter cells at the end of mitosis. It is essential for the final separation of the daughter cells and involved in other important processes, including cell fate, pluripotency, apical-basal polarity, and cilium/lu...
ORGANISM(S): Homo sapiens (Human) 
2019-08-29 | PXD012374 | Pride
Midbody Obritrap Maxquant Silac Cytokinesis Interactome Lc-ms/ms 
GenomicsThe midbody acts as a translationally active membraneless organelle
The midbody acts as a translationally active membraneless organelle
PRJNA555245 | ENA
GenomicsmRNA splicing in midbody is essential for proper cell abscission in mitosis
mRNA splicing in midbody is essential for proper cell abscission in mitosis
PRJNA1114624 | ENA
TranscriptomicsmRNA splicing in midbody is essential for proper cell abscission in mitosis
Midbody is a transient structure assembled in the last step of mitosis and is currently conceptualized as a structural remnant subject to degradation following cytokinesis. However, our findings indicate that midbody regulation is more complicated than original thought. Knockdown spliceosome protein...
ORGANISM(S): Homo sapiens 
2026-01-01 | GSE268080 | GEO
TranscriptomicsThe midbody acts as a translationally active membraneless organelle
mRNAs associated with microtubules during interphase, metaphase and the midbody stage of cytokinesis were sequenced. Selective midbody-localized RNAs were identified and their translational characteristics were studied.
ORGANISM(S): Cricetulus griseus 
2020-07-18 | GSE134476 | GEO
ProteomicsThe Flemmingsome reveals an ESCRT-to-membrane coupling required for cytokinesis
Cytokinesis requires the constriction of ESCRT-III filaments on the midbody side, where abscission occurs. After ESCRT recruitment at the midbody, it is not known how the ESCRT-III machinery localizes to the abscission site. We obtained the proteome of intact, post-abscission midbodies (Flemmingsome...
ORGANISM(S): Homo sapiens (Human) 
2020-05-22 | PXD013219 | Pride
Human Escrt machinery Cytokinesis Midbody Qexactive Lc-ms/ms 
GenomicsIdentification of midbody-enriched RNAs
Identification of midbody-enriched RNAs
PRJNA926481 | ENA
UnknownThe midbody ring scaffolds the abscission machinery in the absence of midbody microtubules.
Not available
S-EPMC3824018 | biostudies-literature
GenomicsNET1 mRNA localization to the midbody is required for ARP2/3-dependent initiation of mitotic abscission
NET1 mRNA localization to the midbody is required for ARP2/3-dependent initiation of mitotic abscission
PRJNA1507294 | ENA
UnknownMidbody Proteins Display Distinct Dynamics during Cytokinesis.
Not available
S-EPMC9656288 | biostudies-literature
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