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TranscriptomicsGene expression profiles of breast cancer subtypes are detectable in histologically normal breast epithelium
Background: We hypothesize that important genomic differences between breast cancer subtypes occur early in carcinogenesis. Therefore, gene expression might distinguish histologically normal breast epithelium (NlEpi) from breasts containing estrogen receptor positive (ER+) compared with estrogen rec...
ORGANISM(S): Homo sapiens 
2010-12-07 | E-GEOD-21947 | biostudies-arrayexpress
TranscriptomicsHistologically normal epithelium from breast cancer patients and cancer-free prophylactic mastectomy patients
Gene expression in histologically normal epithelium from breast cancer patients and cancer-free prophylactic mastectomy patients share a similar profile Introduction: We hypothesized that gene expression in histologically normal epithelium (NlEpi) would differ in breast cancer patients (HN) compared...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-20437 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human solid cancers reveals a precisely regulated gene expression cassette potently modulates metastasis and survival
Successful carcinogenesis involves the integration of both pro- and anti-oncogenic pathways. We postulated that genes critical for balancing these opposing pathways are likely to be precisely controlled in tumors, since even subtle alterations in their activity might cause substantial alterations in...
ORGANISM(S): Homo sapiens 
2008-10-18 | E-GEOD-5364 | biostudies-arrayexpress
UnknownEffect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC4979167 | biostudies-literature
TranscriptomicsTranscription profiling of human normal brain aging reveals sexually dimorphic gene expression
Gene expression profiles were assessed in the hippocampus (HC), entorhinal cortex (EC), superior frontal gyrus (SG), and postcentral gyrus (PCG) across the lifespan of 63 cognitively intact individuals from 20-99 years old. New perspectives on the global gene changes that are associated with brain ...
ORGANISM(S): Homo sapiens 
2008-10-26 | E-GEOD-11882 | biostudies-arrayexpress
TranscriptomicsProbiotic and Prebiotic Supplementation of Antiretroviral Therapy Improves Gastrointestinal Immunity in SIV-infected Macaques
HIV infection results in damage to the gastrointestinal (GI) tract, microbial translocation and immune activation, which are not completely ameliorated with suppression of viremia by antiretroviral (ARV) therapy. Furthermore, increased morbidity and mortality of ARV-treated HIV-infected individuals ...
ORGANISM(S): Macaca nemestrina 
2013-02-06 | E-GEOD-42232 | biostudies-arrayexpress
UnknownImplementation of Recommendations on the Use of Corticosteroids in Severe COVID-19.
Not available
S-EPMC10751594 | biostudies-literature
UnknownEarly Intervention in Patients With Asymptomatic Severe Aortic Stenosis and Myocardial Fibrosis: The EVOLVED Randomized Clinical Trial.
Not available
S-EPMC11519785 | biostudies-literature
UnknownWho, if anyone, may benefit from a total hip arthroplasty after a displaced femoral neck fracture?: a post hoc subgroup analysis of the HEALTH trial.
Not available
S-EPMC9422900 | biostudies-literature
UnknownBurden of disease scenarios by state in the USA, 2022-50: a forecasting analysis for the Global Burden of Disease Study 2021.
Not available
S-EPMC11715278 | biostudies-literature
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