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TranscriptomicsExpression data from primary breast tumors (NUH)
Frozen tissue specimens from primary breast tumors were collected under approved protocols and profiled using Affymetrix U133 series expression microarrays. This cohort was assembled at the National University Hospital (NUH), Singapore in 2003, and profiled at the Genome Institute of Singapore, Micr...
ORGANISM(S): Homo sapiens 
2012-03-30 | E-GEOD-36772 | biostudies-arrayexpress
UnknownLaparoscopic Cytoreduction After Neoadjuvant Chemotherapy in High-Grade Epithelial Ovarian Cancer: A LANCE Randomized Clinical Trial.
Not available
S-EPMC11582931 | biostudies-literature
TranscriptomicsTranscription profiling of human breast cancer samples to generate an expression signature for p53 status
The biological tumor samples (ie, breast tumor specimens) consisted of freshly frozen breast tumors from a population-based cohort of 315 women representing 65% of all breast cancers resected in Uppsala County, Sweden, from January 1, 1987 to December 31, 1989. Estrogen receptor status was determin...
ORGANISM(S): Homo sapiens 
2008-04-04 | E-GEOD-3494 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer tumor samples from Uppsala and Singapore cohorts
Histological grading of breast cancer defines morphological subtypes informative of metastatic potential, although not without considerable inter-observer disagreement and clinical heterogeneity particularly among the moderately differentiated grade II (G2) tumors. We posited that a gene expression ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-4922 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array time series of human MCF7 breast cancer cells treated with estradiol
Using a chromatin immunoprecipitation-paired end diTag cloning and sequencing strategy, we mapped estrogen receptor alpha (ERalpha) binding sites in MCF-7 breast cancer cells. We identified 1,234 high confidence binding clusters of which 94% are projected to be bona fide ERalpha binding regions. Onl...
ORGANISM(S): Homo sapiens 
2009-01-09 | E-GEOD-11352 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of individual bovine nuclear transfer blastocysts
Individual zona free in vitro grown bovine day 7 blastocysts were compared to stage and quality matched nuclear transfer derived blastocysts (fibroblast donor cells).
ORGANISM(S): Bos taurus 
2006-02-14 | E-MEXP-556 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression analysis comparing SKOV3ip1 and the taxane-resistant SKOV3TRip2
We sought to compare mRNA expression profiles between the parental SKOV3ip1 and taxane-resistant SKOV3TRip2 in order to determine what genes are mediating taxane resistance 3 separate collections of each cell line were made, with cells at 75-80% confluence growing on 2-dimentional culture plates, an...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-GEOD-23779 | biostudies-arrayexpress
UnknownQuantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors.
Not available
S-EPMC6611588 | biostudies-literature
TranscriptomicsExpression Profiles of Responders versus Non-Responders with AML or MDS to the Novel Mitochondrial Inhibitor CPI-613
To determine if there are differences in the gene expression profile of peripheral blood mononuclear cells in patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) who responded to CPI-613 when compared to those patients who did not respond we generated gene expression profile...
ORGANISM(S): Homo sapiens 
2014-08-13 | E-GEOD-60350 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human solid cancers reveals a precisely regulated gene expression cassette potently modulates metastasis and survival
Successful carcinogenesis involves the integration of both pro- and anti-oncogenic pathways. We postulated that genes critical for balancing these opposing pathways are likely to be precisely controlled in tumors, since even subtle alterations in their activity might cause substantial alterations in...
ORGANISM(S): Homo sapiens 
2008-10-18 | E-GEOD-5364 | biostudies-arrayexpress
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