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ProteomicsStomatin modulates adipogenesis through ERK pathway and regulates fatty acid uptake and lipid droplet growth
Controlling fatty acid uptake, lipid production and storage, and metabolism of lipid droplets (LDs), is closely related to lipid homeostasis, adipocyte hypertrophy and obesity. We report here that stomatin, a major constituent of lipid rafts, participates in adipogenesis and adipocyte maturation by ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-05 | PXD031866 | Pride
Erk pathway Adipogenesis 3t3-l1 adipocyte-like cell 
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (V. parahaemolyticus-infected spleen metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7996 | MetaboLights
ProteomicsPhosphoproteome of Hepatitis C Virus infected Huh7.5.1 cells
This project enriched and identified phosphoproteins in human hepatocarcinoma 7.5.1 cell line (Huh7.5.1) upon Hepatitis C virus (HCV) infection.
ORGANISM(S): Homo sapiens (Human) Recombinant Hepatitis C virus J6/JFH1-J6 
2016-07-08 | PXD000988 | Pride
Hepatitis c virus Phosphoproteome 
UnknownA long noncoding RNA, lincRNA-Tnfaip3, acts as a coregulator of NF-κB to modulate inflammatory gene transcription in mouse macrophages.
Not available
S-EPMC6191062 | biostudies-literature
ProteomicsDual-Resolving of Positional and Geometric Isomerism of C=Cs via Bifunctional Visible-light-activated Photocycloaddition-Photoisomerization Reaction System
The biological functions of lipids largely depend on their chemicalspatial structures. The position and configuration of C=C bonds are two of the essential attributes that determine the structures of unsaturated lipids. However, simultaneous identification of both attributes remains challenging. Her...
ORGANISM(S): Homo Sapiens Arabidopsis Thaliana 
2022-02-19 | PXD031819 |
ProteomicsER-associated degradation of Eag1 potassium channels by the RING E3 ubiquitin ligase MKRN1: the presence of a dual ubiquitination system
Mutations in the human gene encoding the neuron-specific Eag1 voltage-gated K+ channel are associated with neurodevelopmental diseases, indicating an important role of Eag1 during brain development. A disease-causing Eag1 mutant channel is linked to defective protein stability that involves enhanced...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023984 | Pride
Ring e3 Mkrn1 
UnknownDetecting Key Functional Components Group and Speculating the Potential Mechanism of Xiao-Xu-Ming Decoction in Treating Stroke.
Not available
S-EPMC9136080 | biostudies-literature
UnknownPrognostic value of postoperative serum carcinoembryonic antigen levels in colorectal cancer patients who smoke.
Not available
S-EPMC7274431 | biostudies-literature
UnknownCCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation.
Not available
S-EPMC11303582 | biostudies-literature
UnknownMismatch negativity (MMN) stands at the crossroads between explicit and implicit emotional processing.
Not available
S-EPMC7133097 | biostudies-literature
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