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To search for biomarkers to differentiate Adult-Onset Steroid Sensitive focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). Compared the profiles of glomerular transcriptomes between patients with FSGS and patients with MCD using microarray analysis. This dataset is part of ...
ORGANISM(S): Homo sapiens 
Idiopathic membranous nephropathy and minimal change disease (MCD) transcriptome
Podocyte injury is the hallmark of both focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) and is ultimately reflected in foot process effacement proteinuria. Triggers and pathogenic pathways leading to podocyte cytoskeleton rearrangements are however incompletely explained. ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-03-12 | MSV000097297 | MassIVE
Background: Minimal change disease (MCD) and focal-segmental glomerulosclerosis (FSGS) are immune-mediated glomerular diseases manifesting as nephrotic syndrome. Autoantibodies against the podocyte slit diaphragm protein nephrin were recently identified in a subset of patients with minimal change di...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-27 | PXD047417 | Pride
Background: Minimal change disease (MCD) and focal-segmental glomerulosclerosis (FSGS) are immune-mediated glomerular diseases manifesting as nephrotic syndrome. Autoantibodies against the podocyte slit diaphragm protein nephrin were recently identified in a subset of patients with minimal change di...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-27 | PXD047421 | Pride
Introduction: Minimal change disease (MCD) is a major cause of nephrotic syndrome. With a substantial number of patients requiring long-term immunosuppression leading to significant morbidity, the study aim was to determine MCD glomerular transcriptome to serve as a basis for biomarker discovery and...
ORGANISM(S): Homo sapiens 
2023-01-25 | GSE216841 | GEO
This study aimed to shed light on the potential pathophysiology of MCD by using glomerular proteomic analysis. Shotgun proteomics using label-free quantitative mass spectrometry was performed on formalin-fixed, paraffin-embedded (FFPE) renal biopsies from two groups of samples: control (CTR) and MCD...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-03-12 | MSV000094293 | MassIVE
To search for biomarkers to differentiate Adult-Onset Steroid Sensitive focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD).
ORGANISM(S): Homo sapiens 
2017-01-04 | GSE69814 | GEO
miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue [mRNA, minimal change disease]
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