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ProteomicsMink1 Kinase Regulates Dorsal Mesodermal Cell Fate in the Xenopus Gastrula via HMGA2
Congenital Heart Disease (CHD) is the most common birth defect and leading cause of infant mortality, yet molecular mechanisms explaining CHD remain mostly unknown. Sequencing studies are identifying CHD candidate genes at a brisk rate including MINK1, a serine/threonine kinase. However, a plausible...
ORGANISM(S): Xenopus tropicalis 
2024-05-22 | PXD028827 | Pride
Left right patterning Beta catenin Xenopus Hmga2 Mink1 Wnt signaling Spemann organizer Congenital heart disease Gastrulation 
GenomicsEffect of MINK1 deficiency on gene expression in CD8+ T cells activation
Effect of MINK1 deficiency on gene expression in CD8+ T cells activation
PRJNA1425065 | ENA
GenomicsEffect of MINK1 deficiency on gene expression in CD8+ OT-I TILs
Effect of MINK1 deficiency on gene expression in CD8+ OT-I TILs
PRJNA1425073 | ENA
TranscriptomicsEffect of MINK1 deficiency on gene expression in CD8+ OT-I TILs
The accumulation of ROS in the tumor microenvironment is a major driving factor for immunosuppression. While its detrimental effects on T cell activation are recognized, the precise molecular mechanisms remain unclear. In this study, we identify MINK1 as a ROS-responsive kinase in regulating CD8+ T ...
ORGANISM(S): Mus musculus 
2026-05-14 | GSE319767 | GEO
TranscriptomicsEffect of MINK1 deficiency on gene expression in CD8+ T cells activation
The accumulation of ROS in the tumor microenvironment is a major driving factor for immunosuppression. While its detrimental effects on T cell activation are recognized, the precise molecular mechanisms remain unclear. In this study, we identify MINK1 as a ROS-responsive kinase in regulating CD8+ T ...
ORGANISM(S): Mus musculus 
2026-05-14 | GSE319766 | GEO
UnknownPriming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages.
Not available
S-EPMC8414466 | biostudies-literature
UnknownMink1 regulates spemann organizer cell fate in the xenopus gastrula via Hmga2.
Not available
S-EPMC10116378 | biostudies-literature
UnknownGlucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators.
Not available
S-EPMC8080530 | biostudies-literature
UnknownMisshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.
Not available
S-EPMC3408143 | biostudies-literature
UnknownMulti-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis.
Not available
S-EPMC9408972 | biostudies-literature
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