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TranscriptomicsTranscription profiling of parotid glands from mice with targeted expression of architectural transcription factor HMGA2
Targeted expression of architectural transcription factor HMGA2 in salivary glands of transgenic mice.
ORGANISM(S): Mus musculus 
2007-01-01 | E-MEXP-871 | biostudies-arrayexpress
ProteomicsMink1 Kinase Regulates Dorsal Mesodermal Cell Fate in the Xenopus Gastrula via HMGA2
Congenital Heart Disease (CHD) is the most common birth defect and leading cause of infant mortality, yet molecular mechanisms explaining CHD remain mostly unknown. Sequencing studies are identifying CHD candidate genes at a brisk rate including MINK1, a serine/threonine kinase. However, a plausible...
ORGANISM(S): Xenopus tropicalis 
2024-05-22 | PXD028827 | Pride
Left right patterning Beta catenin Xenopus Hmga2 Mink1 Wnt signaling Spemann organizer Congenital heart disease Gastrulation 
TranscriptomicsHMGA2/TET1/HOXA9 pathway regulates breast cancer growth and metastasis.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-43741 | biostudies-arrayexpress
GenomicsExamination of HMGA2 binding genes in human HMGA2-exogenous overexpressed gastric cancer cells
Examination of HMGA2 binding genes in human HMGA2-exogenous overexpressed gastric cancer cells
PRJNA729973 | ENA
TranscriptomicsMicroRNA expression array of 1833 cells: control vs. HMGA2 shRNA
HMGA2 has been implicated in tumor progression. Identification of microRNAs regulated by HMGA2 helps us to understand how HMGA2 regulates tumor metastasis via its downstream target mircoRNAs and genes. Total RNA was extracted from 1833 cells with control or depleted HMGA2 expression, respectively. E...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-43739 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of MDA-MB-231 cells with HMGA2 knock-down
We have reported that the nuclear protein high mobility group A2 (HMGA2), is required for the induction of EMT by TGF-beta (Thuault et al. J. Cell Biol. 2006). HMGA2 regulates a cohort of transcriptional regulators of the EMT process, such as Snail1 and Twist1 (Thuault et al. J. Biol. Chem. 2008, E-...
ORGANISM(S): Homo sapiens 
2012-02-13 | E-MEXP-3547 | biostudies-arrayexpress
GenomicsHMGA2 project, CRISPR screen
HMGA2 project, CRISPR screen
PRJNA718268 | ENA
TranscriptomicsTranscriptional regulation of myoblasts in HMGA2 KO mice
We sought to identify critical factors regulating muscle stem cell activation and commitment, and determined through loss-of-function analyses that HMGA2 (high mobility group AT-hook 2) is a key regulator of myogenesis both in vitro and in vivo. mRNAs were isolated from Hmga2 -/- and Hmga2 +/+ mice ...
ORGANISM(S): Mus musculus 
2012-12-01 | E-GEOD-41907 | biostudies-arrayexpress
GenomicsHMGA2-driven gene expression in human colorectal DLD-1 cells.
HMGA2-driven gene expression in human colorectal DLD-1 cells.
PRJNA562647 | ENA
TranscriptomicsHMGA2 overexpression
Overexpression of high mobility group AT-hook 2 (HMGA2) associated with truncations of its 3’ untranslated region (UTR) with let-7 micro RNA-complementary sequences have been identified in patients with paroxysmal nocturnal hemoglobinuria (PNH). Here, we generated transgenic mice (∆Hmga2 mice) with ...
ORGANISM(S): Mus musculus 
2011-02-06 | GSE24071 | GEO
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