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ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-04 | MSV000079624 | MassIVE
ProteomicsT-cell derived exosomes released from Multi-Core Granules exhibit potent caspase 3 mediated tumor suppressive activity ( Part II)
Small extracellular vesicles (sEV) derived from cytotoxic T lymphocytes (CTLs) are emerging as potential mediators of antitumor immunity, yet their subcellular origins and functional properties remain incompletely defined. In this study, we investigated the intracellular routes and cytotoxic potenti...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD070419 | Pride
Tetraspanins 10x-expansion Munc13-4 Extracellular vesicles Primary cells Cd8+ t-cells Immunological synapse Multivesicular bodies 
TranscriptomicsRNA sequencing of tumor associated macrophages and T cells in clear cell renal cell carcinoma
Tumor associated macrophages and T cells were characterized in a cohort of 73 ccRCC and 5 healthy donors using mass cytometry. Macrophage and T cell subsets of interest were identified and sorted directly from samples known to contain a high frequency of these subsets. CD8+ PD-1- T cells (n=6), exha...
ORGANISM(S): Homo sapiens 
2017-05-04 | E-MTAB-5640 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq and TCR-seq of Panc02-Fluc model with vehicle, anti PD1-IL2v, PD1, FAP-IL2v and PD1+FAP-IL2v treatment
Differentiating PD-1 + TCF-1 + stem-like CD8 T cells towards a distinct effector T cell population with enhanced anti-tumor and anti-viral efficacy by delivering an engineered IL-2 variant through PD-1 mediated cis-targeting; Single time point at termination (day 3 after 2nd Ab therapy); Tumor model...
ORGANISM(S): Mus musculus 
2022-06-13 | E-MTAB-11773 | biostudies-arrayexpress
UnknownThe nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis.
Not available
S-EPMC3082312 | biostudies-literature
Transcriptomicsmicroarray analysis of bone marrow derived macrophages stimulated with helminth larvae and immune serum
Mouse bone marrow derived macrophages were stimulated with L3 larvae of the helminth Heligmosomoides polygyrus (Hp) (500 L3 /1 mio cells) in the presence or absence of immune serum (1:50 v:v) from challenge-Hp-infected mice.
ORGANISM(S): Mus musculus 
2013-12-31 | E-MEXP-3920 | biostudies-arrayexpress
ProteomicsProteomic phenotyping of stimulated Müller cells uncovers profound pro-inflammatory signaling and antigen-presenting capacity
Müller cells are the main macroglial cells of the retina exerting a wealth of functions to maintain retinal homoeostasis. Upon pathological changes in the retina, they become gliotic with both protective and detrimental consequences. Accumulating data also provide evidence for a pivotal role of Müll...
ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig) 
2022-02-16 | PXD028390 | Pride
Pro-inflammatory Complement system Cytokines. retina Immune response Müller cells Atypical antigen-presenting cell Diabetic retinopathy 
UnknownDepositional Environment of Mio-Pliocene Siwalik Sedimentary Strata from the Darjeeling Himalayan Foothills, India: A Palynological Approach.
Not available
S-EPMC4773139 | biostudies-literature
UnknownT-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses.
Not available
S-EPMC12048687 | biostudies-literature
UnknownT-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses
Not available
S-SCDT-10_1038-S44318-025-00414-3 | biostudies-other
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