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TranscriptomicsFunctional Study of the Chicken microRNAs miR-143 and miR-10a
MicroRNA (miRNA) is a family of small regulatory RNA that post-transcriptionally regulates many biological functions including growth and development. Chicken miR-143 and miR-10a are expressed in both the embryonic and post-hatch chick in a spatio-temporal manner. In order to study the functions of ...
ORGANISM(S): Gallus gallus 
2010-05-16 | E-GEOD-16653 | biostudies-arrayexpress
TranscriptomicsSmall RNA-Seq Reveals similar miRNA Transcriptome in Children and Young Adults with T-ALL and Indicates miR-143-3p as Novel Candidate Tumor Suppressor in This Leukemia
We aimed to identify miRNAs and pathways specifically deregulated in adolescent and young adult (AYA) T-ALL patients. Small RNA-seq showed no major differences between AYA and pediatric T-ALL, but it revealed downregulation of miR-143-3p in T-ALL patients. Prediction algorithms identified several kn...
ORGANISM(S): Homo sapiens 
2022-09-06 | E-MTAB-11987 | biostudies-arrayexpress
TranscriptomicsMicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis
Background: Psoriasis is a systemic inflammatory skin disease. MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that recently have been found in the blood to be relevant as disease biomarkers. Objective: We aimed to explore miRNAs potential as blood biomarkers for psoriasis. Methods:...
ORGANISM(S): Homo sapiens 
2014-06-10 | E-GEOD-55515 | biostudies-arrayexpress
TranscriptomicsmiR-143-5p suppresses breast cancer progression by targeting the HIF-1α-related GLUT1 pathway
Breast cancer (BC) is a commonly identified life-threatening type of cancer and a major cause of death among women worldwide. Several microRNAs (miRs), including miR-143-5p, have been reported to be vital for regulating hallmarks of cancer; however, the effect of miR-143-5p on BC requires further ex...
ORGANISM(S): Homo sapiens 
2022-02-26 | E-MTAB-11160 | biostudies-arrayexpress
TranscriptomicsExpression data from primary hepatocytes isolated from miR-143DOX mice
The contribution of altered posttranscriptional gene silencing (PTGS) to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. We have described that expression of microRNAs (miR)-143 and -145 is dysregulated in genetic and dietary mouse models of obesity. Induce...
ORGANISM(S): Mus musculus 
2011-04-08 | E-GEOD-26460 | biostudies-arrayexpress
GenomicsUnderstanding the role of miRNA-143 (miR-143) in ischemia-induced retinopathy via RNA transcriptome profiling
Understanding the role of miRNA-143 (miR-143) in ischemia-induced retinopathy via RNA transcriptome profiling
PRJNA413139 | ENA
GenomicsImpact of miR-143-3p and miR-145-5p overexpression on human M238P melanoma cells
Impact of miR-143-3p and miR-145-5p overexpression on human M238P melanoma cells
PRJNA721324 | ENA
ProteomicsThe proteome analysis of Human colorectal cancer
Every three samples of pelvic CRC (DLD-1 clone#1-Luc cell) in the control and Chemically-modified miR-143 (CM-miR143) groups, which were frozen in liquid nitrogen, were prepared. Every three samples were resected four times, three days after the administration of the control miRNA or CM-miR143 lipop...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041937 | Pride
Human Protein Mir-143 
TranscriptomicsA Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells]
Long non-coding RNAs (lncRNAs) are a diverse category of transcripts with poor conservation and have expanded greatly in primates, particularly in their brain. We identified a lncRNA, which has acquired 16 microRNA response elements (MREs) for miR-143-3p in the Catarrhini branch of primates. This ln...
ORGANISM(S): Homo sapiens 
2016-06-23 | E-GEOD-73982 | biostudies-arrayexpress
TranscriptomicsmRNA-seq and AGO2-RIP-seq of JURKAT T-cell acute lymphoblastic leukemia cell line upon overexpression of hsa-miR-143-3p
The aim of this study was to investigate the effect of hsa-miR-143-3p on global gene expression in T-cell acute lymphoblastic leukemia (T-ALL) and to unravel its direct target genes. For this purpose we selected Jurkat T-ALL cell line characterized by low expression of this miRNA. The cells were tra...
ORGANISM(S): Homo sapiens 
2024-08-31 | E-MTAB-13462 | biostudies-arrayexpress
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