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TranscriptomicsTrastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells
Objective: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC ...
ORGANISM(S): Homo sapiens 
2012-06-02 | E-GEOD-38415 | biostudies-arrayexpress
ProteomicsSpecific milk composition in miR-30b-transgenic mice associated to offspring early gut maturation with lasting consequences on their growth
Milk composition is complex and includes numerous components essential for the offspring growth and development. Besides a high abundance of the miR-30b microRNA, milk produced by the transgenic mouse model of miR-30b-mammary deregulation displays significant changes in its fatty acid profils. Moreo...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-09 | PXD037629 | Pride
Milk composition Gut barrier Early maturation Mice Mir-30b 
ProteomicsImpact of milk on the offspring early gut maturation
Milk composition is complex and includes numerous components essential for the offspring growth and development. Besides a high abundance of the miR-30b microRNA, milk produced by the transgenic mouse model of miR-30b-mammary deregulation displays significant changes in its fatty acid profils. Moreo...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-24 | PXD037626 | Pride
Milk composition Gut barrier Early maturation Mice Mir-30b 
GenomicsHepatic steatosis accelerates vascular endothelial dysfunction by extracellular vesicle-mediated activation of miR-30b-5p/Elovl5 axis
Hepatic steatosis accelerates vascular endothelial dysfunction by extracellular vesicle-mediated activation of miR-30b-5p/Elovl5 axis
PRJNA1458779 | ENA
GenomicsTrastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells
Objective: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC ...
ORGANISM(S): Homo sapiens 
2012-06-03 | GSE38415 | GEO
UnknownmiR-30b-5p inhibits osteoblast differentiation through targeting BCL6.
Not available
S-EPMC8942429 | biostudies-literature
GenomicsHepatic steatosis accelerates vascular endothelial dysfunction by extracellular vesicle-mediated activation of miR-30b-5p/Elovl5 axis
Background & Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is an independent risk factor for cardiovascular disease (CVD), although the mechanism underlying this association remains unclear. Extracellular vesicles (EVs) are biological nanoparticles that play critical roles i...
ORGANISM(S): Mus musculus 
2026-05-28 | GSE329384 | GEO
UnknownmiR-24, miR-30b, and miR-142-3p regulate phagocytosis in myeloid inflammatory cells.
Not available
S-EPMC4323870 | biostudies-literature
UnknownmiR-30b-5p acts as a tumor suppressor microRNA in esophageal squamous cell carcinoma.
Not available
S-EPMC6687993 | biostudies-literature
UnknownThe expression and clinical significance of miR-30b-3p and miR-125b-1-3p in patients with periodontitis.
Not available
S-EPMC9354350 | biostudies-literature
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