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ProteomicsMouse Liver LC-MS/MS LNA miR-676 treated dbdb mice
Over 40 % of microRNAs are located in introns of coding genes, and many intronic microRNAs are co-regulated with their host genes. In such cases of co-regulation, the products of host genes and their intronic microRNAs can cooperate to coordinately regulate biologically important pathways. Therefore...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-14 | PXD006573 | Pride
Lc-msms Mouse Mir-676 Dbdb mice Liver 
TranscriptomicsDistinctive Profile of IsomiR Expression and Novel MicroRNAs in Rat Heart Left Ventricle
MicroRNAs (miRNAs) are single-stranded non-coding RNAs that negatively regulate target gene expression through mRNA cleavage or translational repression. There is mounting evidence that they play critical roles in heart disease. The expression of known miRNAs in the heart has been studied at length ...
ORGANISM(S): Rattus norvegicus 
2014-03-28 | E-GEOD-56300 | biostudies-arrayexpress
GenomicsmicroRNA microarray profiling in the livers of control db/+ and diabetic db/db mice
Analysis revealed a set of 13 microRNAs to be significantly altered between livers of control db/+ and diabetic db/db mice. Of these, miR-34a, miR-107, miR-378, miR-378*, miR-31, miR-31*, miR-151-5p, miR-676, miR-22, miR-93, let-7b were up-regulated and let-7e and miR-227 were down-regulated. A tota...
ORGANISM(S): Mus musculus 
2011-12-22 | GSE17035 | GEO
GenomicsIdentification of translational microRNA biomarker candidates for ketoconazole-induced liver injury using next-generation sequencing
Drug induced liver injury (DILI) is a leading cause of acute liver failure. Reliable and translational biomarkers are needed for early detection of DILI. microRNAs (miRNAs) have received wide attention as a novel class of potential DILI biomarkers. However, it is unclear how DILI drugs other than ac...
ORGANISM(S): Rattus norvegicus 
2020-10-23 | GSE159200 | GEO
TranscriptomicsWhole genome resequencing of spleen in mice model
Eight-week-old female BALB/c mice were randomly divided into three groups (20 per group), the negative control group and positive control group were injected i.p. with normal saline (NS) or OVA (0.05 mg/day) for three times (days 1, 3, and 5), and one group was added in which the miR-676-3P mimic wa...
ORGANISM(S): Mus musculus 
2026-03-31 | GSE186567 | GEO
GenomicsProfiling the circulating miRNAs in mice exposed to gram-positive and gram-negative bacteria by Illumina small RNA deep sequencing
We profiled the expression of circulating microRNAs (miRNAs) in mice exposed to gram-positive and gram-negative bacteria using Illumina small RNA deep sequencing. Recombinant-specific gram-negative pathogen Escherichia coli (Xen14) and gram-positive pathogen Staphylococcus aureus (Xen29) were used t...
ORGANISM(S): Mus musculus 
2014-08-19 | GSE60492 | GEO
UnknownA functional screen with metformin identifies microRNAs that regulate metabolism in colorectal cancer cells.
Not available
S-EPMC8861101 | biostudies-literature
UnknownAnalysis of extracellular vesicle miRNA profiles in heart failure.
Not available
S-EPMC7339231 | biostudies-literature
UnknownIdentification of Translational microRNA Biomarker Candidates for Ketoconazole-Induced Liver Injury Using Next-Generation Sequencing.
Not available
S-EPMC7855383 | biostudies-literature
GenomicsDistinctive Profile of IsomiR Expression and Novel MicroRNAs in Rat Heart Left Ventricle
MicroRNAs (miRNAs) are single-stranded non-coding RNAs that negatively regulate target gene expression through mRNA cleavage or translational repression. There is mounting evidence that they play critical roles in heart disease. The expression of known miRNAs in the heart has been studied at length ...
ORGANISM(S): Rattus norvegicus 
2014-03-28 | GSE56300 | GEO
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