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MetabolomicsThe Impacts of Sortase A and the 4'-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA), which affects S. mutans...

2021-10-06 | MTBLS1812 | MetaboLights
TranscriptomicsLiver Regeneration Gene Signature in Hepatitis B virus (HBV)-Associated Acute Liver Failure Identified by Gene Expression Profiling
The liver has inherent regenerative capacity via mitotic division of mature hepatocytes. However, if the hepatic loss is massive or mature hepatocyte proliferation is impaired by chronic liver injury, HSPC are activated to support liver regeneration. Access to liver tissue from 4 patients who underw...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-38941 | biostudies-arrayexpress
UnknownGenotypes of glycoprotein B gene among the Indian symptomatic neonates with congenital CMV infection.
Not available
S-EPMC6704666 | biostudies-literature
TranscriptomicsNF-?B Activation Controls Phagolysosome Fusion-Mediated killing of Mycobacteria by Macrophages
Mycobacterium smegmatis is a model non-pathogenic mycobacterium that is efficiently killed by macrophages. Here, we explore the role of NF-?B in the innate immune response, focusing in detail on the mechanisms of the first killing period (1-4h) of M. smegmatis which coincides with phagosome-lysosome...
ORGANISM(S): Mus musculus 
2007-10-23 | E-GEOD-8999 | biostudies-arrayexpress
ProteomicsAldehydes alter TGF-b signaling and induce obesity and cancer
Obesity and fatty liver diseases—metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH)—affect over one-third of the global population and are exacerbated in individuals with reduced functional aldehyde dehydrogenase 2 (ALDH2), ob...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055145 | Pride
Sptbn1 aldehydes 4-hydroxynonenal 
UnknownTargeted delivery of doxorubicin-loaded poly (ε-caprolactone)-b-poly (N-vinylpyrrolidone) micelles enhances antitumor effect in lymphoma.
Not available
S-EPMC3979807 | biostudies-literature
UnknownIdentification of potent cholecystokinin-B receptor antagonists: synthesis, molecular modeling and anti-cancer activity against pancreatic cancer cells.
Not available
S-EPMC6071963 | biostudies-literature
UnknownLong-Term Engraftment of ESC-Derived B-1 Progenitor Cells Supports HSC-Independent Lymphopoiesis.
Not available
S-EPMC6409422 | biostudies-literature
TranscriptomicsDe Novo Assembly and Characterization of Stress Transcriptome in a salinity-Tolerant Variety CS52 of Brassica juncea
Oilseed mustard, Brassica juncea, exhibits high levels of genetic variability for salinity tolerance. To obtain the global view of transcriptome and investigate the molecular basis of salinity tolerance in a salt-tolerant variety CS52 of B. juncea, we performed transcriptome sequencing of control an...
ORGANISM(S): Brassica juncea 
2015-02-28 | E-GEOD-66389 | biostudies-arrayexpress
UnknownMLL1 Promotes IL-7 Responsiveness and Survival during B Cell Differentiation.
Not available
S-EPMC5909838 | biostudies-literature
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