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Characterization of NEURL4 as a novel mitochondrial ART enzyme and identification of its potential targets.
ORGANISM(S): Homo sapiens (Human) 
2022-02-04 | PXD029538 | Pride
Mitochondrial PARP1 Regulates NAD+-dependent Poly ADP-ribosylation on Mitochondrial Nucleoids
Nicotinamide adenine dinucleotide (NAD+) is a vital small molecule with important redox capacity in oxidative phosphorylation (OXPHOS) and a key co-factor in various enzymatic reactions. The recent identification of the mitochondrial NAD+ transporter SLC25A51 provides strong evidence for a direct re...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD031373 | Pride
ADP-ribosylome analysis in human U20S cells and mouse muscle tissues
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-09-08 | PXD013918 | Pride
ADP-ribosylation of mitochondrial proteins is mediated by Neuralized-like protein 4 (NEURL4)
Cardiomyocyte mitochondrial mono-ADP-ribosylation dictates cardiac tolerance to sepsis by configuring bioenergetic reserve
Notch signaling plays both oncogenic and tumor suppressor roles, depending on cell type. In contrast to T cell acute lymphoblastic leukemia (T-ALL), where Notch activation promotes leukemogenesis, induction of Notch signaling in B-ALL leads to growth arrest and apoptosis. The Notch target Hairy/Enha...
ORGANISM(S): Homo sapiens 
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