Sort   by:  
 Page size 
ProteomicsPyruvate-supported flux through medium chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles
Even-chain acylcarnitine (AC) metabolites, most of which are generated as byproducts of incomplete fatty acid oxidation (FAO), are viewed as biomarkers of mitochondrial lipid stress attributable to one or more metabolic bottlenecks in the beta-oxidation pathway. The origins and functional implicatio...
ORGANISM(S): Mus Musculus (mouse) 
PXD040326 | JPOST Repository
ProteomicsNeuralized-like protein 4 (Neurl4) mediates ADP-ribosylation of mitochondrial proteins
Characterization of NEURL4 as a novel mitochondrial ART enzyme and identification of its potential targets.
ORGANISM(S): Homo sapiens (Human) 
2022-02-04 | PXD029538 | Pride
Mitochondrial proteins Hela Neurl4 Adp-ribosylation Mitochondrial art 
GenomicsFirst Art
Recovering ancient human DNA from rock art and cave walls
PRJEB97209 | ENA
TranscriptomicsHIV Infection and Antiretroviral Therapy Have Divergent Effects on Mitochondria in Adipose Tissue
Exploratory microarray analysis identified significant changes in gene expression in adipose tissue. These included changes in genes regulating lipid and steroid metabolic processes and electron carrier activity in HIV-infected patients receiving antiretroviral therapy (ART). Additional genes invo...
ORGANISM(S): Homo sapiens 
2011-07-07 | E-GEOD-30310 | biostudies-arrayexpress
TranscriptomicsLimb immobilization induces a coordinate down-regulation of mitochondrial and other metabolic pathways in men and women
Advancements in animal models and cell culture techniques have been invaluable in the elucidation of molecular events and mechanisms regulating muscle atrophy. However, few studies have examined muscle atrophy in humans using modern experimental techniques. The purpose of this study was to examine a...
ORGANISM(S): Homo sapiens 
2009-02-21 | E-GEOD-14901 | biostudies-arrayexpress
TranscriptomicsArtemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice
Calorie restriction is known to extend lifespan among organisms by a debating mechanism underlying nitric oxide-driven mitochondrial biogenesis. We report here that nitric oxide generators including artemisinin, sodium nitroprusside, and L-arginine mimics calorie restriction and resembles hydrogen p...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-65993 | biostudies-arrayexpress
UnknownMitochondrial DNA Damage and Brain Aging in Human Immunodeficiency Virus.
Not available
S-EPMC8282328 | biostudies-literature
UnknownMitochondrial Functions Are Compromised in CD4 T Cells From ART-Controlled PLHIV.
Not available
S-EPMC8129510 | biostudies-literature
TranscriptomicsParkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration
Parkinson's disease (PD) is an adult-onset movement disorder of largely unknown etiology. We have previously shown that loss-of-function mutations of the mitochondrial protein kinase PINK1 (PTEN induced putative kinase 1) cause the recessive PARK6 variant of PD. Now we generated a PINK1 deficient mo...
ORGANISM(S): Mus musculus 
2014-11-04 | E-GEOD-60413 | biostudies-arrayexpress
UnknownROS-Induced Mitochondrial Dysfunction in CD4 T Cells from ART-Controlled People Living with HIV.
Not available
S-EPMC10224005 | biostudies-literature
Sort   by:  
 Page size