Mitochondrial extracellular vesicles

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Unknown (416)
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Mass spectrometry assay (5)
Proteogenomics (2)
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Gel-based experiment (1)
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Instrument Platform

Liquid Chromatography MS - alternating - hilic (4)
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Q Exactive HF (2)
Gas Chromatography MS - positive (2)
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HPC (1)
NEXTflex small RNA library preparation kit v4; TruSeq exome RNA library preparation kit (Illumina); High Sensitivity DNA ScreenTape D1000 (1)
QIAzol and miRNeasy micro kits; Bioanalyzer TapeStation 2100; Qubit microRNA assay (1)
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Liquid Chromatography MS - positive - hilic (1)

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2012 (2)
2016 (2)
2005 (1)
2019 (1)
2018 (1)

CHEBI ID

CHEBI:15741 (3)
CHEBI:30915 (3)
CHEBI:17992 (2)
CHEBI:422 (2)
CHEBI:32816 (2)
CHEBI:30797 (2)
CHEBI:17154 (2)
CHEBI:16347 (2)
CHEBI:15756 (2)
CHEBI:47979 (1)
CHEBI:189710 (1)
CHEBI:41378 (1)
CHEBI:4735 (1)
CHEBI:28542 (1)
CHEBI:27376 (1)
CHEBI:170017 (1)
CHEBI:15889 (1)
CHEBI:52153 (1)
CHEBI:47878 (1)
CHEBI:32368 (1)
CHEBI:68566 (1)
CHEBI:68572 (1)
CHEBI:17665 (1)
CHEBI:28013 (1)
CHEBI:27693 (1)
CHEBI:191640 (1)
CHEBI:16891 (1)
CHEBI:28623 (1)
CHEBI:25351 (1)
CHEBI:36096 (1)

Metabolite Name

Adenine (4)
Inosine (4)
IMP (3)
AMP (3)
ATP (3)
L-Alanine (3)
Uracil (3)
ADP (3)
Ornithine (3)
Oxaloacetate (3)
UMP (3)
Lactate (3)
Guanosine (3)
2,3-DPG (2)
D-Ribulose-5-phosphate (2)
D-Glucose-1-phosphate (2)
Guanosine-diphosphate (2)
Flavin-mononucleotide (2)
Isocitric-acid (2)
Dihydroxyacetone-phosphate (2)
6-Phosphogluconic-acid (2)
Phosphoenolpyruvic-acid (2)
Fructose-1,6-bisphosphate (2)
Cyclic-AMP (2)
C-di-AMP (2)
Fumaric-acid (2)
Citric-acid (2)
3-phenyllactic-acid (2)
Cysteic-acid (2)
Glucuronic-acid (2)

First Public Date

2026 (17)
2025 (12)
2020 (7)
2024 (4)
2022 (3)
2023 (2)
2021 (2)
2016 (2)
2019 (1)
2018 (1)
2015 (1)
2014 (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

RNA-seq of coding RNA (3)
Transcription profiling by array (2)
Unknown experiment type (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (98)
2023 (67)
2022 (63)
2024 (57)
2021 (36)
2020 (27)
2026 (20)
2019 (15)
2018 (9)
2017 (9)
2015 (7)
2016 (7)
2012 (2)
2014 (2)
2011 (2)
2005 (1)

Lab affiliation

Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, Guangdong, China. (2)
Division of Gastroenterology and Hepatology, School of Medicine, University of Colorado Anschutz Medical Campus,Colorado, USA (2)
1Research Institute of the McGill University Health Centre, Montreal, QC, Canada 2Department of Pathology, McGill University, Montreal, QC, Canada 3Gerald Bronfman Department of Oncology, McGill University, Montreal, QC, Canada (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Assistant Professor, Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center (1)
Assistant Professor, Departments of Oncology & Pathology, McGill University Principal Investigator, Cancer Research Program, MUHC-RI 1001 Decarie Blvd, EM2.2218 514.934.1934 ext 76307 Montréal, Canada (1)
Associate Professor, Cedars-Sinai Medical Center, Surgery (1)
Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark (1)
Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID), University of Cambridge, Cambridge, UK (1)
Cedars-Sinai Medical Center (1)
Cellular & Molecular Metabolism Laboratory, Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University. (1)
Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, MA, United States (1)
Center of Basic Science, Biomedical Research Foundation of the Academy of Athens, Athens, Greece (1)
Department for BioMedical Research (DBMR), University of Bern, 3008 Bern, Switzerland (1)
Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands (1)
Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi (1)
Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, 3810-193 Aveiro, Portugal. (1)
Department of Molecular Biology, Cristea Lab, Princeton University, Princeton, NJ, US (lab head) (1)
Department of Molecular and Clinical Medicine, Institueof Medicine,Sahlgrenska Academy at Gothenburg University (1)
Department of Neurology, Johns Hopkins University School of Medicine (1)
Dept. of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. (1)
Eye Institute of Shandong First Medical University，Eye Hospital of Shandong First Medical University (Shandong Eye Hospital), Jinan, China (1)
Faculty of Pharmacy, University of Helsinki University Medical Center Groningen / University of Groningen, The Netherlands (1)
German Center for Diabetes Research, Partner Düsseldorf, München-Neuherberg, Germany (1)
Head of the Curie Institute Mass Spectrometry Platform (1)
Head of the Laboratory for Vascular Biology, Department of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation (1)
Institute of Cell Biology, University of Bern, 3012 Bern, Switzerland (1)
Italian National Institute of Health - Department of Neuroscience (1)
Korea University College of Medicine, Seoul, Republic of Korea (1)
Krefting Research Centre, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (1)

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Cross-Species Mitochondrial Rescue by Gastrodia elata-Derived Extracellular Vesicles Protects the Stressed Mammalian Heart

In this study, we developed Gastrodia elata (G. elata)-derived extracellular vesicles (GE-EVs) to achieve functional rescue of the stressed mammalian heart. Using RBM24 phosphorylation-deficient (S181A, A/A) mice, we demonstrated that GE-EVs have a profound cross-species rescue effect on mitochondri...

2026-04-09 | MTBLS14245 | MetaboLights

Cross-Species Mitochondrial Rescue by Gastrodia elata-Derived Extracellular Vesicles Protects the Stressed Mammalian Heart

2026-04-09 | MTBLS14243 | MetaboLights

Proteomic and metabolomic profiling of extracellular vesicles produced by human gut archaea

Gastrointestinal bacteria interact with the host and each other through various mechanisms, including the production of extracellular vesicles (EVs). However, the composition and potential roles of EVs released by gut archaea are poorly understood. Here, we study EVs produced by four strains of h...

2025-07-01 | MTBLS12422 | MetaboLights

Parallel single-cell metabolic analysis and extracellular vesicle profiling reveal vulnerabilities with prognostic significance in acute myeloid leukemia (Metabolomic analysis on extracellular vesicles)

Acute myeloid leukemia (AML) is an aggressive disease with a high relapse rate. In this study, we map the metabolic profile of CD34+(CD38low/-) AML cells and the extracellular vesicle signatures in circulation from AML patients at diagnosis. CD34+ AML cells display high antioxidant glutathione le...

2024-12-04 | MTBLS11746 | MetaboLights

Parallel single-cell metabolic analysis and extracellular vesicle profiling reveal vulnerabilities with prognostic significance in acute myeloid leukemia (Lipidomic analysis on extracellular vesicles)

2024-12-04 | MTBLS11523 | MetaboLights

A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate

Mitochondrial fatty acid oxidation (FAO) is essential for hematopoietic stem cell (HSC) self-renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate remains unknown. Here, we show that within the hematopoietic lineage, HSCs have the largest mitochondrial NADPH pools, w...

2025-07-07 | MTBLS6401 | MetaboLights

Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer

Selective autophagy of mitochondria is known to promote survival and progression of cancer cells in various malignancies, including triple-negative breast cancer (TNBC). Here, we investigate the essential metabolic adaptations that support mitochondrial quality control in cancer cells with the ai...

2025-09-30 | MTBLS13037 | MetaboLights

Mitochondrial RNA in Alzheimer’s Disease Circulating Extracellular Vesicles

PRJNA644390 | ENA

Intracellular and extracellular microRNAs expressed by HEK293T cells

MicroRNAs (miRNAs) are a class of small RNA molecules that regulate expression of specific mRNA targets. They can be released from cells, often encapsulated within extracellular vesicles (EVs), and therefore have the potential to mediate intercellular communication. It has been suggested that certai...

ORGANISM(S): Homo sapiens

2012-06-25 | E-GEOD-38916 | biostudies-arrayexpress

Proteomics Characterization of Mitochondrial-Derived Vesicles Under Oxidative Stress

Mitochondria share attributes of vesicular transport with their bacterial ancestors given their ability to form mitochondrial-derived vesicles (MDVs). MDV formation enhances with stress and has been explored for its potential role in mitochondrial-directed cellular and extracellular signalling. Alth...

ORGANISM(S): Rattus norvegicus (Rat)

2021-09-08 | PXD020110 | Pride

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