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Mitotic bookmarking transcription factors (TFs) are thought to mediate rapid and accurate post-mitotic gene reactivation. However, the loss of individual bookmarking TFs often leads to the deregulation of only a small proportion of their mitotic targets, raising doubts on the significance and import...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-20 | PXD038950 | Pride
Mitotic bookmarking by SWI/SNF subunits
Mixed Lineage Leukemia (MLL) and its metazoan Trithorax orthologs have been linked with the epigenetic maintenance of transcriptional activity. To identify mechanisms by which MLL perpetuates active transcription in dividing cells, we investigated its role during M-phase of the cell cycle. Unlike ot...
ORGANISM(S): Homo sapiens 
Mitotic bookmarking redundancy by nuclear receptors mediates robust post-mitotic reactivation of the pluripotency network
The control of transcriptional memory by stable mitotic bookmarking
GATA2 mitotic bookmarking is required for definitive haematopoiesis [ChIP-seq]
GATA2 mitotic bookmarking is required for definitive hematopoiesis [scRNA-seq]
Topoisomerase I (TOP1) is a functional mitotic interactor of the bookmarking factor HNF1B
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