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ProteomicsImpact of TDP-43 CR Deletion on the Synaptosome Proteome of the Mouse Brain
Synaptic loss is a prominent and early pathological feature of all neurodegenerative diseases, including ALS and other TDP-43-associated neurodegenerative disorders. To investigate neuron-specific pathways affected by TDP-43 CR deletion, we conducted a quantitative mass spectrometry analysis of syna...
ORGANISM(S): Mus musculus (Mouse) 
2026-05-22 | PXD060626 | Pride
Tdp-43 Mouse brain Synaptosome 
ProteomicsSILACE - Enhanced energy metabolism contributes to the extended life span of calorie-restricted Caenorhabditis elegans
WT worm is unlabeled and eat-2 knock out worm is labeled with 13C6-Lysine. Mixed 1 to 1 by wet weight. Fractionated to 20 fractions by off line 2D-LC.
ORGANISM(S): Caenorhabditis elegans 
2012-12-06 | PRD000517 | Pride
ProteomicsProteomic analysis of brain tissues from 6- and 20-month-old wild-type and TDP-43 ΔTBM mice
Mass spectrometry–based proteomic profiling of total brain proteins from 6- and 20-month-old wild-type and TDP-43 ΔTBM mice, enabling analysis of disease-associated and age-dependent protein expression changes.
ORGANISM(S): Mus musculus (Mouse) 
2026-09-18 | PXD072777 | Pride
Proteomics Tdp-43 Mouse Neurodegeneration 
ProteomicsProteome analysis of the retina from RhoQ344X/+ mouse
Retinal proteomes from wild-type and RhoQ344X mutant mice at postnatal day 35 were analyzed by label-free quantitative proteomics to understand proteomic change caused by the rhodopsin mutation.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-11-08 | MSV000093339 | MassIVE
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