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TranscriptomicsMapping of MLE and MSL2 using iCLIP
Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long non-coding RNAs (lncRNAs) for transcriptional up-regulation of the entire X-chromosome. Here, UV cross-linking followed by deep sequencing (iCLIP) show that two enzymes in the Male-Specific Lethal complex, MLE ...
ORGANISM(S): Drosophila melanogaster 
2013-07-18 | E-MTAB-1669 | biostudies-arrayexpress
GenomicsMycolicibacterium senegalense strain:MLE
Mycolicibacterium senegalense strain:MLE Genome sequencing and assembly
PRJNA288077 | ENA
GenomicsMLE ChIP-seq
Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) was carried out on wild-type Schneider (S2) cells using specific MLE antibodies to identify binding sites for MLE in the Drosophila genome
ORGANISM(S): Drosophila melanogaster 
2013-10-30 | E-MTAB-1705 | biostudies-arrayexpress
TranscriptomicsMLE HITS-CLIP in Drosophila S2 cells
HITS-CLIP was carried out on wild-type Schneider (S2) cells using specific MLE antibodies to identify binding sites for MLE in the Drosophila transcriptome
ORGANISM(S): Drosophila melanogaster 
2013-10-30 | E-MTAB-1706 | biostudies-arrayexpress
GenomicsMLE ChIP-seq
MLE ChIP-seq
PRJEB4008 | ENA
TranscriptomicsRNAseq of the protease transcriptome of primary murine alveolar epithelial cells type II (AECII) and the murine lung cells MLE-15
RNAseq of primary murine alveolar epithelial cells type II (AECII) and the murine lung cells MLE-15 in order to identify potential candidates of trypsin-like proteases capable to cleave the influenza surface glycoprotein hemaglutinine (HA). AECII cells do support the cleavage of HA while MLE-15 cell...
ORGANISM(S): Mus musculus 
2020-03-27 | E-MTAB-8571 | biostudies-arrayexpress
ProteomicsStructural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless
RNA unwinding by DExH-type helicases underlies most RNA metabolism and function. It remains unresolved if and how the basic unwinding reaction of helicases is regulated by auxiliary domains. We explored the interplay between the RecA and auxiliary domains of the RNA helicase maleless (MLE) from Dros...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-11-27 | PXD045725 | Pride
Helicase Qexactivehf Cl-ms Mle Rna Cx-ms Crosslinking Drosophila melanogaster 
GenomicsMLE HITS-CLIP in Drosophila S2 cells
MLE HITS-CLIP in Drosophila S2 cells
PRJEB4010 | ENA
GenomicsTranscriptome sequencing of Serpine1-overexpression MLE-12 cells
Transcriptome sequencing of Serpine1-overexpression MLE-12 cells
PRJNA876753 | ENA
GenomicsMapping of MLE and MSL2 using iCLIP
Mapping of MLE and MSL2 using iCLIP
PRJEB3406 | ENA
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