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ProteomicsThe MNV-1 ProPol precursor Cleaves a Novel Site in the NS1-2 Protein
Human noroviruses (HuNV) are members of the Caliciviridae family and are a significant cause of gastroenteritis worldwide. Cell culture models are challenging for studying the intracellular replication of HuNV, with murine norovirus (MNV) routinely used to study norovirus replication. Norovirus geno...
ORGANISM(S): Murine norovirus 1 
2026-06-08 | PXD074184 | Pride
Norovirus Tails Non-structural polyprotein Protease cleavage 
TranscriptomicsTranscription profiling of mouse MNV-1 infected and mock-infected RAW 264.7 cells.
Noroviruses have been widely recognized for their importance as causative agents of non-bacterial gastroenteritis. Mouse norovirus is the only representative of the norovirus genus, family Caliciviridae, able to grow in cell culture. The aim of this study is to describe the differences in the expres...
ORGANISM(S): Mus musculus 
2009-04-25 | E-GEOD-12518 | biostudies-arrayexpress
GenomicsExamining the role of murine norovirus (MNV)-infection on intraepithelial lymphocytes (IELs).
Examining the role of murine norovirus (MNV)-infection on intraepithelial lymphocytes (IELs).
PRJNA842399 | ENA
TranscriptomicsExpression data from MNV-specific CD8 T cells
Mouse norovirus (MNV) causes acute or chronic infection in immunocompetent hosts, but the CD8 T cell determinants of viral persistence versus clearance are unknown. We used microarrays to interrogate the transcriptional program on MNV-specific CD8 T cells from the spleen and intestine at days 8, 15,...
ORGANISM(S): Mus musculus 
2017-07-24 | GSE101429 | GEO
ProteomicsAnalysis of the nascent proteome during murine norovirus infection
SILAC- and AHA-labelling analysis of Raw264.7 cells infected with MNV-1 at MOI=10TCID50/cell and harvested at 6.5 and 10.5 hours post infection. AP-MS enrichment of AHA-labelled nascent polypeptides represents the first quantitative neoproteomics analysis of norovirus infected cells.
ORGANISM(S): Mus musculus (Mouse) 
2021-07-02 | PXD025169 | Pride
Raw264.7 Aha Mnv Silac 
TranscriptomicsRNA-sequencing of murine norovirus (MNV) infection and loxoribine (Lox) stimulation in RAW264.7 macrophages
This study aimed to generate a comprehensive analysis of changes in the transcriptome following MNV infection. Furthermore, we aimed to perform a differential gene expression analysis between MNV infection and loxoribine (tlr7 agonist) treatment to delineate features of the host modified directly by...
ORGANISM(S): Mus musculus 
2017-02-14 | GSE94843 | GEO
GenomicsWhole mesenteric lymph nodes (mLN) RNA-seq from MNV or Reovirus infected C57BL/6 mice
Whole mesenteric lymph nodes (mLN) RNA-seq from MNV or Reovirus infected C57BL/6 mice
PRJNA482460 | ENA
TranscriptomicsMurine Norovirus Effect on Cells
Changes in gene expression on MNV infection of RAW264.7 cells RAW264.7 cells were infected with MNV-1 at a multiplicity of infection of 1, or mock infected, for 12 hours
ORGANISM(S): Mus musculus 
2015-04-19 | E-GEOD-61562 | biostudies-arrayexpress
TranscriptomicsExamining the role of murine norovirus (MNV)-infection on intraepithelial lymphocytes (IELs).
We examined how MNV-infection affects the population and function of IELs in vivo.
ORGANISM(S): Mus musculus 
2022-07-01 | GSE204822 | GEO
TranscriptomicsRNA-sequencing of longitudinal murine norovirus (MNV) infection in RAW264.7 mouse macrophages
The transcriptome has an abundance of information about the function of individual cells, tissues and an organism in general. Characterising the transcriptome of virus infected cells can illuminate features of the viral-host relationship that are important for pathogenesis. This study broadly aimed ...
ORGANISM(S): Mus musculus 
2017-02-14 | GSE94821 | GEO
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