Sort   by:  
 Page size 
TranscriptomicsRibosomal biogenesis genes play an essential and p53-independent role in pancreas development
Analysis of transcriptional profiles in Sbds(ATG) MO-injected embryos with and without coinjection of p53(ATG) MO. We identified a large number of changes in transcript abundance associated with loss of Sbds. Among the 24,278 annotated zebrafish genes in the platform, 4,892 significantly differenti...
ORGANISM(S): Danio rerio 
2012-07-16 | E-GEOD-39399 | biostudies-arrayexpress
ProteomicsCompositional analysis of extracellular aggregates in the eyes of patients with exfoliation syndrome and exfoliation glaucoma.
Exfoliation syndrome (XFS) is a condition characterized by the production of insoluble fibrillar aggregates (exfoliation material; XFM) in the eye and elsewhere. Many patients with XFS progress to exfoliation glaucoma (XFG), a significant cause of global blindness. We used quantitative mass spectrom...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026764 | Pride
Human Exfoliation syndrome Shotgun proteomics Psr-ohsu Lens capsule Aqueous humor Tmt labeling Quantitative proteomics Exfoliation glaucoma 
UnknownEffects of tumor grade and dexamethasone on myeloid cells in patients with glioma.
Not available
S-EPMC6204983 | biostudies-literature
TranscriptomicsEffects of Lipocalin 2 (Lcn2), iron, and the bacterial siderophore Enterobactin on A549 respiratory cell gene expression
Iron is essential for many cellular processes and is required by bacteria for replication. To acquire iron from the host, pathogenic Gram-negative bacteria secrete siderophores, including Enterobactin (Ent). However, Ent is bound by the host protein Lipocalin 2 (Lcn2), preventing bacterial reuptake ...
ORGANISM(S): Homo sapiens 
2014-07-03 | E-GEOD-54962 | biostudies-arrayexpress
UnknownThe structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.
Not available
S-EPMC5899615 | biostudies-literature
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
ProteomicsMycoplasma pneumoniae processes functionally diverse proteins (N-Terminiome & Surfaceome)
Mycoplasma pneumoniae is a significant cause of pneumonia, particularly in children, the elderly and the immunocompromised, and post infection sequelae affecting organ sites distant to the respiratory tract are common. It is also a model pathogen where extensive ‘omics’ studies have been conducted t...
ORGANISM(S): Mycoplasma pneumoniae Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2021-05-01 | PXD022356 | Pride
Pneumonia Affinity N-terminiome Mycoplasma Surfaceome 
UnknownPhase II Intergroup Trial of Alisertib in Relapsed and Refractory Peripheral T-Cell Lymphoma and Transformed Mycosis Fungoides: SWOG 1108.
Not available
S-EPMC4500834 | biostudies-literature
TranscriptomicsCharacterization of CD57+PD1- CD4 T cells
We have identified a CD57+PD1- CD4 T cell phenotype at the time of transplantation that strongly correlates with subsequesnt development of belatacept-resistant rejection. In this study, we used microarray to determine which genes were upregulated in CD57+ compared to CD57- CD4 T cells. Peripheral b...
ORGANISM(S): Homo sapiens 
2016-01-08 | E-GEOD-64805 | biostudies-arrayexpress
UnknownImpaired autophagy in macrophages promotes inflammatory eye disease.
Not available
S-EPMC5066937 | biostudies-literature
Sort   by:  
 Page size