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Mouse embyronic fibroblasts (MEFs) were depleted for transcription factor Specificity Factor 2 (Sp2) via Cre-Recombinase, harvested either 7 days or several weeks post infection and their expression profile compared to mock-infected MEFs.
ORGANISM(S): Mus musculus 
After overexpression and knockdown of both described novel miRs nmiR-1 and nmiR-2 in BL cell lines (SU-DHL4 for nmiR-1 and Raji for nmiR-2), we performed regular RNA-Seq (including Mock controls for all cell lines) to identify their direct and indirect downstream mRNA targets.
Arabidopsis thaliana plants were grown from seeds. Roots of 7 day old plants were inoculated with L. bicolor. After 2 days, leaves were harvested, shock frozen in liquid nitrogen and prepared for RNA extraction
ORGANISM(S): Arabidopsis thaliana 
Arabidopsis thaliana plants were grown from seeds. Roots of 9 day old plants were inoculated with L. bicolor. After 4 weeks, two T. ni larvae per plant fed for 24 h. Leaves were subsequently harvested, shock frozen in liquid nitrogen and prepared for RNA extraction
ORGANISM(S): Arabidopsis thaliana 
Zaire ebolavirus (ZEBOV) infections are associated with high lethality in primates. ZEBOV primarily targets mononuclear phagocytes, which are activated upon infection and secrete mediators believed to trigger initial stages of pathogenesis. The characterization of the responses of target cells to ZE...
ORGANISM(S): Homo sapiens 

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
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