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MetabolomicsThe phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 inhibitor 3PO is a modulator of neutrophil metabolism, ROS production and NET release
Neutrophils are key effector leukocytes of the innate immune system and play a pivotal role in defending the host against microbial infections. Recent studies have identified a crucial link between glycolysis and neutrophil cellular functions. We have investigated in human neutrophils, the intricate...
2025-08-14 | MTBLS6215 | MetaboLights
MetabolomicsDistinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator b-glucan in a two-case ex vivo non-small cell lung cancer study
Not available
ORGANISM(S): Homo sapiens 
ST000367 | MetabolomicsWorkbench
ProteomicsThe novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L
Here, by state-of-the-art mass spectrometry-based quantitative proteomic technology, we systematically screened the potential neo-substrates of a novel thalidomide derived cereblon modulator CC-885.
ORGANISM(S): Homo Sapiens 
2020-01-11 | PXD017071 |
TranscriptomicsModulator of Apoptosis 1 (MOAP-1) is a highly regulated tumor suppressor protein
Modulator of apoptosis 1 (MOAP-1) is a BH3-like protein that plays key roles in both the intrinsic and extrinsic modes of cell death or apoptosis. It is an integral partner to the tumor suppressor Ras association domain family 1A (RASSF1A) and functions to activate the Bcl-2 family pro-apoptotic pro...
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-43990 | biostudies-arrayexpress
GenomicsOverexpression of the EMT modulator SNAI1 in HPC7 cells
Overexpression of the EMT modulator SNAI1 in HPC7 cells
PRJNA622443 | ENA
GenomicsCaSR modulator in neuroblastoma model
CaSR modulator in neuroblastoma model
PRJNA297180 | ENA
GenomicsNMDA receptor positive allosteric modulator induced genome wide gene expression changes in neuronal cultures
NMDA receptor positive allosteric modulator induced genome wide gene expression changes in neuronal cultures
PRJNA578282 | ENA
TranscriptomicsThe delta subunit of RNA polymerase, RpoE, is a global modulator of Streptococcus mutans environmental adaptation
Transcriptional profiling of S. mutans rpoE knockout mutant comparing to the wild type. The mutation of rpoE cause dramatic changes in phenotypes. The goal is to determine the genes affected by rpoE. The delta subunit of RNA polymerase, RpoE, is wide spread in low G+C Gram-positive bacteria and is t...
ORGANISM(S): Streptococcus mutans UA159 
2010-09-21 | E-GEOD-22333 | biostudies-arrayexpress
GenomicsEMF1 functions as a 3D chromatin modulator in Arabidopsis
EMF1 functions as a 3D chromatin modulator in Arabidopsis
PRJEB60957 | ENA
Genomicsbulk RNAseq of Ccd18-Co cell line treated with cytokine mix and/or epigenetic modulator
bulk RNAseq of Ccd18-Co cell line treated with cytokine mix and/or epigenetic modulator
PRJNA1321909 | ENA
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