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TranscriptomicsProfiling of hypothalamus tissue from the F2 M16xICR mouse cross.
We profiled gene expression in hypothalamus tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, liver or...
ORGANISM(S): Mus musculus 
2010-06-22 | E-GEOD-13745 | biostudies-arrayexpress
TranscriptomicsProfiling of adipose tissue from the F2 M16xICR mouse cross.
We profiled gene expression in adipose tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, adipose or ad...
ORGANISM(S): Mus musculus 
2009-10-25 | E-GEOD-13746 | biostudies-arrayexpress
TranscriptomicsProfiling of liver tissue from the F2 M16xICR mouse cross.
We profiled gene expression in liver tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, liver or liver ...
ORGANISM(S): Mus musculus 
2009-10-25 | E-GEOD-13752 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CEPH panel members to investigate natural variation in human gene expression
We measured the baseline expression levels of genes in members of the CEPH pedigrees using Affymetrix Human Genome Focus Arrays. Arrays were analyzed using MAS 5.0 software (Affymetrix).
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1485 | biostudies-arrayexpress
TranscriptomicsIdentification of Genes and Networks Driving Cardiovascular and Metabolic Phenotypes in a Mouse F2 Intercross
To identify the genes and pathways that underlie cardiovascular and metabolic phenotypes we performed an integrated analysis of a mouse C57BL/6J x A/J F2 (B6AF2) cross by relating genome-wide gene expression data from adipose, kidney, and liver tissues to physiological endpoints measured in the popu...
ORGANISM(S): Mus musculus 
2011-01-13 | E-GEOD-25506 | biostudies-arrayexpress
TranscriptomicsmRNA expression of 131 cancer cell lines
131 human cancer cell lines' mRNA expression profiles have been characterized. Keywords: Cell Line Comparison mRNA samples obtained from 131 human cancer cell lines were hybridized to Agilent Human 3.0 A1 arrays and gene expression (mlratio) was measured relative to a common reference RNA pool (Hum...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13598 | biostudies-arrayexpress
TranscriptomicsMapping the Genetic Architecture of Gene Expression in Human Liver
To uncover the genetic determinants affecting expression in a metabolically active tissue relevant to the study of obesity, diabetes, atherosclerosis, and other common human diseases, we profiled 427 human liver samples on a comprehensive gene expression microarray targeting greater than 40,000 tran...
ORGANISM(S): Homo sapiens 
2008-05-07 | E-GEOD-9588 | biostudies-arrayexpress
TranscriptomicsExpression profile of liver samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24293 | biostudies-arrayexpress
TranscriptomicsExpression profile of omental adipose samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24294 | biostudies-arrayexpress
TranscriptomicsExpression profile of subcutaneous adipose samples from subjects at the time of Roux en Y gastric bypass surgery.
To map the genetics of gene expression in metabolically relevant tissues and investigate the diversity of expression SNPs (eSNPs) in multiple tissues from the same individual, we collected four tissues from approximately 1,000 patients undergoing Roux-en-y gastric bypass and clinical traits associat...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-24297 | biostudies-arrayexpress
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