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TranscriptomicsResponse of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity
Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety, health and performance of the crewmembers. As a ubiquitous environmental organism that is occasionally part of the human flora, Pseudomonas aeruginosa could pose a health hazar...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2010-07-29 | E-GEOD-16970 | biostudies-arrayexpress
TranscriptomicsTranscriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen
Characterization of bacterial behavior in the microgravity environment of spaceflight is of importance towards risk assessment and prevention of infectious disease during long-term missions. Further, this research field unveils new insights into connections between low fluid-shear regions encountere...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2011-06-28 | E-GEOD-22684 | biostudies-arrayexpress
TranscriptomicsGold induction of C. metallidurans CH34
Whole-genome expression microarray experiments were conducted to assess the response of C. metallidurans CH34 to aqueous Au(III)-chloride and identify possible biochemical pathways for Au detoxification. Four microarray experiments were conducted to assess gold response at low, medium and high Au(II...
ORGANISM(S): Ralstonia metallidurans CH34 
2010-06-20 | E-GEOD-14049 | biostudies-arrayexpress
TranscriptomicsToxicogenomic response of Rhodospirillum rubrum S1H to the model micropollutant triclosan
Aiming at the development of a micropollutant biosensor in the frame of the Micro-Ecological Life Support System Alternative (MELiSSA), a pilot study was initiated to identify triclosan (TCS)-responsive biomarker genes in the MELiSSA carbon-mineralizing microorganism, Rhodospirillum rubrum S1H. TCS ...
ORGANISM(S): Rhodospirillum rubrum 
2010-05-19 | E-GEOD-16189 | biostudies-arrayexpress
TranscriptomicsHeavy metal resistance in Cupriavidus metallidurans CH34 is governed by an intricate transcriptional network.
Background: The high number of heavy metal resistance genes in the soil bacterium Cupriavidus metallidurans CH34 makes it an interesting model organism to study microbial responses to heavy metals. Results: In this study the transcriptional response of this bacterium was measured after challenging i...
ORGANISM(S): Cupriavidus metallidurans CH34 
2011-06-28 | E-GEOD-23876 | biostudies-arrayexpress
TranscriptomicsVariation in genomic islands contribute to genome plasticity in Cupriavidus metallidurans
Different Cupriavidus metallidurans strains isolated from metal-contaminated and other anthropogenic environments were genotypically and phenotypically compared with C. metallidurans type strain CH34. The latter is well-studied for its resistance to a wide range of metals, which is carried for a sub...
ORGANISM(S): Cupriavidus metallidurans CH34 
2014-01-23 | E-GEOD-36303 | biostudies-arrayexpress
TranscriptomicsMetal resistant bacterium Cupriavidus metallidurans CH34
Metal resistant bacterium Cupriavidus metallidurans CH34 uses non-conventional proteins to combat oxidative stress Keywords: Cupriavidus metallidurans; hydrogen peroxide; oxidative stress; Two-condition experiments. Comparing samples after challenging with oxidative stress versus non-induced samples...
ORGANISM(S): Cupriavidus metallidurans CH34 
2014-09-13 | E-GEOD-24094 | biostudies-arrayexpress
TranscriptomicsMechanisms of adaptation to stress and control of virulence in Pseudomonas aeruginosa: the OxyR regulons
Oxidative stress caused by exposure to reactive oxygen species (ROS), is a major challenge for aerobic and especially anaerobic organisms. Bacteria coordinate the response to oxidative stress through the LysR-type transcriptional regulator (LTTR) OxyR. Extensive studies have focused on the classical...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2013-12-13 | E-GEOD-33871 | biostudies-arrayexpress
TranscriptomicsResponse of Rhodospirillum rubrum S1H to three pharmaceuticals
The present study explores the potential of compound-specific gene-upregulation profiles in the ubiquitous purple nonsulfur bacterium Rhodospirillum rubrum S1H as biomarkers for exposure to surface water contaminants, i.e. high production-volume pharmaceuticals. Even though the pharmaceuticals [i.e....
ORGANISM(S): Rhodospirillum rubrum 
2013-08-23 | E-GEOD-23794 | biostudies-arrayexpress
TranscriptomicsIntegrative analysis of the biodegradation of acetone/isopropanol by Cupriavidus metallidurans CH34: proposal of a metabolic pathway
Various environmental bacteria were adapted to the presence of toxic and recalcitrant organic solvents. Cupriavidus metallidurans CH34, a β-proteobacterium that was found in industrial environments is known as a bacterial model to study heavy metal resistance. Interestingly, genome screening of CH3...
ORGANISM(S): Cupriavidus metallidurans CH34 
2015-08-31 | E-GEOD-33578 | biostudies-arrayexpress
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