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UnknownDiscovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.
Not available
S-EPMC3264597 | biostudies-literature
ProteomicsOncogenic mutations in the Gα-protein GNA11 convey a shorter disease specific survival and are more strongly associated with loss of BAP1 and chromosomal alterations than GNAQ mutations in uveal melanoma
Mutations of the Gα-proteins GNAQ and GNA11 are found in 85-90% of uveal melanomas (UMs). We analyzed the association of GNAQ and GNA11 mutations with disease-specific survival, gene expression profiles, and cytogenetic alterations in 219 UMs. Our analysis showed a shorter disease-specific survival ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-22 | PXD030217 | Pride
Bap1 Gna11 Gnaq Metastasis risk Asap1 
TranscriptomicsEGFR and MEK pathway signature RNA-Seq datasets
EGFR and MEK pathways were activated alone or in combination in human mammary epithelial cells. We profiled the pathway gene expression signatures using RNA-Seq. mRNA was extracted from human mammary epithelial cells overexpressing EGFR gene, MEK gene, or EGFR and MEK genes in combination (or GFP co...
ORGANISM(S): Homo sapiens 
2015-03-05 | E-GEOD-59765 | biostudies-arrayexpress
ProteomicsStandardization of mitochondrial proteomics v2 NP
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-14 | MSV000081329 | MassIVE
ProteomicsStandardization of mitochondrial proteomics
Comparison of the extraction performances of three different mitochondria enrichment protocols (differential centrifugation, sucrose gradient, a commercial kit based on surfactants) on ten different cell lines. Samples were analysed on several instrumental platforms. Mitochondrial pellets were lysed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-30 | MSV000081121 | MassIVE
UnknownPatterns of care of brain tumor-related epilepsy. A cohort study done in Italian Epilepsy Center.
Not available
S-EPMC5513411 | biostudies-literature
UnknownThe role of immune suppression in COVID-19 hospitalization: clinical and epidemiological trends over three years of SARS-CoV-2 epidemic.
Not available
S-EPMC10513414 | biostudies-literature
UnknownThe ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?
Not available
S-EPMC9755784 | biostudies-literature
UnknownBurnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey.
Not available
S-EPMC10810224 | biostudies-literature
UnknownTocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial.
Not available
S-EPMC7576974 | biostudies-literature
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