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ProteomicsEffect of Sec61 inhibitor mycolactone on the proteome of the MutuDC dendritic cell line
Here we used a newly identified Sec61 blocker, mycolactone, to analyze Sec61 contribution to antigen cross presentation, ERAD and transport of internalized antigens into the cytosol in dendritic cells. Shotgun proteomics were used to asses the broad-ranging effects of Sec61 blockade on dendritic cel...
ORGANISM(S): Mus musculus (Mouse) 
2017-07-11 | PXD006103 | Pride
Mouse mutudc dendritic mycolactone sec61 ms/ms lfq 
ProteomicsEffect of Sec61 inhibitor mycolactone on the proteome of the MED17.11 neuronal cell line
Mycolactone is a mycobacteria-derived macrolide that blocks the biogenesis of a large array of secreted and transmembrane proteins through potent inhibition of the Sec61 translocon. Here, we used quantitative proteomics to delineate the direct and indirect effects of mycolactone-mediated Sec61 block...
ORGANISM(S): Mus musculus (Mouse) 
2018-06-26 | PXD007770 | Pride
Sec61 Mycolactone Sensory neurons 
UnknownComparison of machine learning and human prediction to identify trauma patients in need of hemorrhage control resuscitation (ShockMatrix study): a prospective observational study.
Not available
S-EPMC12205608 | biostudies-literature
UnknownLow incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients.
Not available
S-EPMC7445552 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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